P34022: Ran-specific GTPase-activating protein

General Information

Protein names	- Ran-specific GTPase-activating protein - HpaII tiny fragments locus 9a protein - Ran-binding protein 1 - RANBP1
Gene names	Ranbp1
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	P34022

13 N-termini

6 C-termini

5 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAAAKDSHED HDTSTENADE SNHDPQFEPI VSLPEQEIKT LEEDEEELFK MRAKLFRFAS
        70         80         90        100        110        120
ENDLPEWKER GTGDVKLLKH KEKGTIRLLM RRDKTLKICA NHYITPMMEL KPNAGSDRAW
       130        140        150        160        170        180
VWNTHADFAD ECPKPELLAI RFLNAENAQK FKTKFEECRK EIEEREKKGP GKNDNAEKVA
       190        200
EKLEALSVRE AREEAEEKSE EKQ

Isoforms

Sequence View

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

13 N-termini - 6 C-termini - 5 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P34022-2-unknown	MAAAKD...	1		inferred from similarity	unknown	UniProtKB		inferred from uniprot (by similarity)
P34022-2-unknown	MAAAKD...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P34022-2-Acetylation	AAAKDS...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P34022-2-Acetylation	AAAKDS...	2	acetylation-	inferred from similarity	unknown	UniProtKB		inferred from uniprot (by similarity)
P34022-30-unknown	IVSLPE...	30		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33531
P34022-35-unmodified	EQEIKT...	35			N-TAILS		Overall CM.	Prudova A.: Multiplex N-terminome analysis of MMP-2 and MMP-9...	20305284
P34022-38-unknown	IKTLEE...	38		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33532
P34022-40-unmodified	TLEEDE...	40			N-TAILS		Overall CM.	Prudova A.: Multiplex N-terminome analysis of MMP-2 and MMP-9...	20305284
P34022-41-unknown	LEEDEE...	41		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33533
P34022-51-unknown	MRAKLF...	51		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSMUSP00000055288
P34022-51-unknown	MRAKLF...	51		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSMUSP00000138996
P34022-58-unmodified	FASEND...	58			N-TAILS		Overall CM.	Kleifeldt O. et al.: Isotopic labeling of terminal amines in complex samples identifies...	20208520
P34022-61-unmodified	ENDLPE...	61			N-TAILS		Overall CM.	Prudova A.: Multiplex N-terminome analysis of MMP-2 and MMP-9...	20305284
P34022-127-unmodified	DFADEC...	127			N-TAILS		Overall CM.	Prudova A.: Multiplex N-terminome analysis of MMP-2 and MMP-9...	20305284
P34022-143-unknown	LNAENA...	143		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33534
P34022-144-unknown	NAENAQ...	144		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC28867

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...PQFEPI	29	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33531
...LPEQEI	37	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33532
...QEIKTL	40	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33533
...LAIRFL	142	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33534
...AIRFLN	143	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28867
...SEEKQ	203	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MMP2_MOUSE	29	FEPI.\|.IVSL	inferred from experiment	unknown	MEROPS		Merops MMP2_MOUSE -> RANG_MOUSE @29
MMP2_MOUSE	37	EQEI.\|.IKTL	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
MMP2_MOUSE	40	IKTL.\|.LEED	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
MMP2_MOUSE	142	IRFL.\|.LNAE	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
CATD_MOUSE	143	RFLN.\|.NAEN	inferred from experiment	unknown	MEROPS		Merops CATD_MOUSE -> RANG_MOUSE @143

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)