TopFIND 4.0

P34884: Macrophage migration inhibitory factor

General Information

Protein names	- Macrophage migration inhibitory factor - MIF - 5.3.2.1 - Delayed early response protein 6 - DER6 - Glycosylation-inhibiting factor - GIF - L-dopachrome isomerase - L-dopachrome tautomerase - 5.3.3.12 - Phenylpyruvate tautomerase
Gene names	Mif
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	P34884

10

N-termini

6

C-termini

9

Cleavages

0

Substrates

Sequence

10 20 30 40 50 60
MPMFIVNTNV PRASVPEGFL SELTQQLAQA TGKPAQYIAV HVVPDQLMTF SGTNDPCALC
70 80 90 100 110
SLHSIGKIGG AQNRNYSKLL CGLLSDRLHI SPDRVYINYY DMNAANVGWN GSTFA

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

10 N-termini - 6 C-termini - 9 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P34884-2-unknown	PMFIVN...	2		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P34884-2-unknown	PMFIVN...	2			N-TAILS		Overall CM.	auf dem Keller U.: A statistics-based platform for quantitative N-terminome...	20305283
P34884-2-unmodified	PMFIVN...	2			N-TAILS		Overall CM.	Prudova A.: Multiplex N-terminome analysis of MMP-2 and MMP-9...	20305284
P34884-4-unknown	FIVNTN...	4		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC28868
P34884-5-unknown	IVNTNV...	5		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC28869
P34884-5-unknown	IVNTNV...	5		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29929
P34884-5-unknown	IVNTNV...	5		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33535
P34884-9-unknown	NVPRAS...	9		inferred from electronic annotation	unknown	TISdb		inferred from TISdb
P34884-37-unknown	YIAVHV...	37		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33536
P34884-48-unknown	MTFSGT...	48		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC31495
P34884-65-unknown	IGKIGG...	65		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29930
P34884-80-unknown	LCGLLS...	80		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29931
P34884-81-unknown	CGLLSD...	81		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29932

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...GKPAQY	36	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33536
	...VPDQLM	47	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC31495
	...CSLHSI	64	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29930
	...NYSKLL	79	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29931
	...YSKLLC	80	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29932
	...GSTFA	115	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATD_MOUSE	3	MPMF.\|.FIVN	inferred from experiment	unknown	MEROPS		Merops CATD_MOUSE -> MIF_MOUSE @3
CATD_MOUSE	4	PMFI.\|.IVNT	inferred from experiment	unknown	MEROPS		Merops CATD_MOUSE -> MIF_MOUSE @4
CATE_MOUSE	4	PMFI.\|.IVNT	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> MIF_MOUSE @4
MMP2_MOUSE	4	PMFI.\|.IVNT	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
MMP2_MOUSE	36	PAQY.\|.YIAV	inferred from experiment	unknown	MEROPS		Merops MMP2_MOUSE -> MIF_MOUSE @36
CBPA6_MOUSE	47	DQLM.\|.MTFS	inferred from experiment	unknown	MEROPS	Fricker LD	Lyons PJ et al.:Substrate specificity of human ... (M14.018)	20855895,
CATE_MOUSE	64	LHSI.\|.IGKI	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> MIF_MOUSE @64
CATE_MOUSE	79	SKLL.\|.LCGL	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> MIF_MOUSE @79
CATE_MOUSE	80	KLLC.\|.CGLL	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> MIF_MOUSE @80

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)