P35613: Basigin
Protein names | - Basigin - 5F7 - Collagenase stimulatory factor - Extracellular matrix metalloproteinase inducer - EMMPRIN - Leukocyte activation antigen M6 - OK blood group antigen - Tumor cell-derived collagenase stimulatory factor - TCSF - CD147 |
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Gene names | BSG |
Organism | Homo sapiens |
Protease Family | |
Protease ID | |
Chromosome location | |
UniProt ID | P35613 |
7
N-termini
3
C-termini
2
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MAAALFVLLG FALLGTHGAS GAAGFVQAPL SQQRWVGGSV ELHCEAVGSP VPEIQWWFEG
70 80 90 100 110 120
QGPNDTCSQL WDGARLDRVH IHATYHQHAA STISIDTLVE EDTGTYECRA SNDPDRNHLT
130 140 150 160 170 180
RAPRVKWVRA QAVVLVLEPG TVFTTVEDLG SKILLTCSLN DSATEVTGHR WLKGGVVLKE
190 200 210 220 230 240
DALPGQKTEF KVDSDDQWGE YSCVFLPEPM GTANIQLHGP PRVKAVKSSE HINEGETAML
250 260 270 280 290 300
VCKSESVPPV TDWAWYKITD SEDKALMNGS ESRFFVSSSQ GRSELHIENL NMEADPGQYR
310 320 330 340 350 360
CNGTSSKGSD QAIITLRVRS HLAALWPFLG IVAEVLVLVT IIFIYEKRRK PEDVLDDDDA
370 380
GSAPLKSSGQ HQNDKGKNVR QRNSS
Isoforms
- Isoform 2 of Basigin - Isoform 3 of Basigin - Isoform 4 of BasiginSequence View
10 20 30 40 50 60
MAAALFVLLG FALLGTHGAS GAAGFVQAPL SQQRWVGGSV ELHCEAVGSP VPEIQWWFEG
70 80 90 100 110 120
QGPNDTCSQL WDGARLDRVH IHATYHQHAA STISIDTLVE EDTGTYECRA SNDPDRNHLT
130 140 150 160 170 180
RAPRVKWVRA QAVVLVLEPG TVFTTVEDLG SKILLTCSLN DSATEVTGHR WLKGGVVLKE
190 200 210 220 230 240
DALPGQKTEF KVDSDDQWGE YSCVFLPEPM GTANIQLHGP PRVKAVKSSE HINEGETAML
250 260 270 280 290 300
VCKSESVPPV TDWAWYKITD SEDKALMNGS ESRFFVSSSQ GRSELHIENL NMEADPGQYR
310 320 330 340 350 360
CNGTSSKGSD QAIITLRVRS HLAALWPFLG IVAEVLVLVT IIFIYEKRRK PEDVLDDDDA
370 380
GSAPLKSSGQ HQNDKGKNVR QRNSS
10 20 30 40 50 60
MAAALFVLLG FALLGTHGAS GAAGFVQAPL SQQRWVGGSV ELHCEAVGSP VPEIQWWFEG
70 80 90 100 110 120
QGPNDTCSQL WDGARLDRVH IHATYHQHAA STISIDTLVE EDTGTYECRA SNDPDRNHLT
130 140 150 160 170 180
RAPRVKWVRA QAVVLVLEPG TVFTTVEDLG SKILLTCSLN DSATEVTGHR WLKGGVVLKE
190 200 210 220 230 240
DALPGQKTEF KVDSDDQWGE YSCVFLPEPM GTANIQLHGP PRVKAVKSSE HINEGETAML
250 260 270 280 290 300
VCKSESVPPV TDWAWYKITD SEDKALMNGS ESRFFVSSSQ GRSELHIENL NMEADPGQYR
310 320 330 340 350 360
CNGTSSKGSD QAIITLRVRS HLAALWPFLG IVAEVLVLVT IIFIYEKRRK PEDVLDDDDA
370 380
GSAPLKSSGQ HQNDKGKNVR QRNSS
10 20 30 40 50 60
MAAALFVLLG FALLGTHGAS GAAGFVQAPL SQQRWVGGSV ELHCEAVGSP VPEIQWWFEG
70 80 90 100 110 120
QGPNDTCSQL WDGARLDRVH IHATYHQHAA STISIDTLVE EDTGTYECRA SNDPDRNHLT
130 140 150 160 170 180
RAPRVKWVRA QAVVLVLEPG TVFTTVEDLG SKILLTCSLN DSATEVTGHR WLKGGVVLKE
190 200 210 220 230 240
DALPGQKTEF KVDSDDQWGE YSCVFLPEPM GTANIQLHGP PRVKAVKSSE HINEGETAML
250 260 270 280 290 300
VCKSESVPPV TDWAWYKITD SEDKALMNGS ESRFFVSSSQ GRSELHIENL NMEADPGQYR
310 320 330 340 350 360
CNGTSSKGSD QAIITLRVRS HLAALWPFLG IVAEVLVLVT IIFIYEKRRK PEDVLDDDDA
370 380
GSAPLKSSGQ HQNDKGKNVR QRNSS
Protein Neighborhood
Domains & Features
7 N-termini - 3 C-termini - 2 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
P35613-1-unknown | MAAALF... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt68219 | |||
P35613-22- | AAGFVQ... | 22 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1SDBJurkat_Mix | 23264352 | |||
P35613-22-unknown | AAGFVQ... | 22 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
P35613-210-unknown | MGTANI... | 210 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt68220 | |||
P35613-210-unknown | MGTANI... | 210 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC21597 | |||
P35613-210-unknown | MGTANI... | 210 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt102919 | |||
P35613-210-unknown | MGTANI... | 210 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt102920 | |||
P35613-212-unknown | TANIQL... | 212 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt182704 | |||
P35613-212-unknown | TANIQL... | 212 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt182703 | |||
P35613-212-unknown | TANIQL... | 212 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt182705 | |||
P35613-212- | TANIQL... | 212 | N-TAILS | Overall Laboratory | Lange_Huesgen_et_al-RBC | ||||
P35613-215-unknown | IQLHGP... | 215 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC21600 | |||
P35613-215-unknown | IQLHGP... | 215 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt137964 | |||
P35613-215-unknown | IQLHGP... | 215 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt142350 | |||
P35613-215-unknown | IQLHGP... | 215 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt195770 |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...FLPEPM | 209 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC21597 | |||
...FLPEPM | 209 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt125262 | |||
...MGTANI | 214 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC21600 | |||
...MGTANI | 214 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt120973 | |||
...MGTANI | 214 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt125542 | |||
...QRNSS | 385 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
...QRNSS | 385 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt63838 | |||
...QRNSS | 385 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt63839 | |||
...QRNSS | 385 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt63837 |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
MMP14_HUMAN | 209 | PEPM.|.MGTA | inferred from experiment | unknown | MEROPS | Yan L | Tang Y et al.:Tumor-stroma interaction: posit... (M10.014) | 14985463, |
MMP14_HUMAN | 214 | TANI.|.IQLH | inferred from experiment | unknown | MEROPS | Yan L | Tang Y et al.:Tumor-stroma interaction: posit... (M10.014) | 14985463, |
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
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