P36873: Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

General Information

Protein names	- Serine/threonine-protein phosphatase PP1-gamma catalytic subunit - PP-1G - 3.1.3.16 - Protein phosphatase 1C catalytic subunit
Gene names	PPP1CC
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P36873

6 N-termini

3 C-termini

1 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform Gamma-2 of Serine/threonine-protein phosphatase PP1-gamma catalytic subunit - Isoform 2 of Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

Sequence View

        10         20         30         40         50         60
MADLDKLNID SIIQRLLEVR GSKPGKNVQL QENEIRGLCL KSREIFLSQP ILLELEAPLK
        70         80         90        100        110        120
ICGDIHGQYY DLLRLFEYGG FPPESNYLFL GDYVDRGKQS LETICLLLAY KIKYPENFFL
       130        140        150        160        170        180
LRGNHECASI NRIYGFYDEC KRRYNIKLWK TFTDCFNCLP IAAIVDEKIF CCHGGLSPDL
       190        200        210        220        230        240
QSMEQIRRIM RPTDVPDQGL LCDLLWSDPD KDVLGWGEND RGVSFTFGAE VVAKFLHKHD
       250        260        270        280        290        300
LDLICRAHQV VEDGYEFFAK RQLVTLFSAP NYCGEFDNAG AMMSVDETLM CSFQILKPAE
       310        320
KKKPNATRPV TPPRGMITKQ AKK         10         20         30         40         50         60
MADLDKLNID SIIQRLLEVR GSKPGKNVQL QENEIRGLCL KSREIFLSQP ILLELEAPLK
        70         80         90        100        110        120
ICGDIHGQYY DLLRLFEYGG FPPESNYLFL GDYVDRGKQS LETICLLLAY KIKYPENFFL
       130        140        150        160        170        180
LRGNHECASI NRIYGFYDEC KRRYNIKLWK TFTDCFNCLP IAAIVDEKIF CCHGGLSPDL
       190        200        210        220        230        240
QSMEQIRRIM RPTDVPDQGL LCDLLWSDPD KDVLGWGEND RGVSFTFGAE VVAKFLHKHD
       250        260        270        280        290        300
LDLICRAHQV VEDGYEFFAK RQLVTLFSAP NYCGEFDNAG AMMSVDETLM CSFQILKPAE
       310        320
KKKPNATRPV TPPRGMITKQ AKK

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

6 N-termini - 3 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P36873-2-unknown	MADLDK...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P36873-1-unknown	MADLDK...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt85840
P36873-2-Acetylation	ADLDKL...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P36873-2-Acetylation	ADLDKL...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
P36873-2-Acetylation	ADLDKL...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
P36873-2-Acetylation	ADLDKL...	2	acetylation-		N-TAILS		Overall Laboratory	Lange_Huesgen_et_al-RBC
P36873-2-Acetylation	ADLDKL...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt110070
P36873-27-unknown	NVQLQE...	27		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt172737
P36873-27-	NVQLQE...	27			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P36873-207-unknown	SDPDKD...	207		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC5824
P36873-207-unknown	SDPDKD...	207		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt146805

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
...CDLLWS	206	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC5824
...CDLLWS	206	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt130128
...KQAKK	323	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
...KQAKK	323		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...KQAKK	323		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,
...KQAKK	323		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...KQAKK	323		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATL1_HUMAN	206	LLWS.\|.SDPD	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)