P42208: Septin-2

General Information

Protein names	- Septin-2 - Neural precursor cell expressed developmentally down-regulated protein 5 - NEDD-5
Gene names	Sept2
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	P42208

9 N-termini

12 C-termini

6 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MSKQQPTQFI NPETPGYVGF ANLPNQVHRK SVKKGFEFTL MVVGESGLGK STLINSLFLT
        70         80         90        100        110        120
DLYPERIIPG AAEKIERTVQ IEASTVEIEE RGVKLRLTVV DTPGYGDAIN CRDCFKTIIS
       130        140        150        160        170        180
YIDEQFERYL HDESGLNRRH IIDNRVHCCF YFISPFGHGL KPLDVAFMKA IHNKVNIVPV
       190        200        210        220        230        240
IAKADTLTLK ERERLKKRIL DEIEEHSIKI YHLPDAESDE DEDFKEQTRL LKASIPFSVV
       250        260        270        280        290        300
GSNQLIEAKG KKVRGRLYPW GVVEVENPEH NDFLKLRTML ITHMQDLQEV TQDLHYENFR
       310        320        330        340        350        360
SERLKRGGRK VENEDMNKDQ ILLEKEAELR RMQEMIARMQ AQMQMQMQGG DSDSGALGQH

V

Isoforms

Sequence View

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Evidence Codes:

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Evidence Names:

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Protein Neighborhood

Domains & Features

9 N-termini - 12 C-termini - 6 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P42208-1-unknown	MSKQQP...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P42208-2-Acetylation	SKQQPT...	2	acetylation-		N-TAILS		Overall CM.	Kleifeldt O. et al.: Isotopic labeling of terminal amines in complex samples identifies...	20208520
P42208-2-Acetylation	SKQQPT...	2	acetylation-		N-TAILS		Overall CM.	Prudova A.: Multiplex N-terminome analysis of MMP-2 and MMP-9...	20305284
P42208-9-unknown	FINPET...	9		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33554
P42208-41-unknown	MVVGES...	41		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSMUSP00000118621
P42208-41-unknown	MVVGES...	41		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSMUSP00000127276
P42208-180-unknown	VIAKAD...	180		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33555
P42208-239-unknown	VVGSNQ...	239		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC34625
P42208-246-unknown	IEAKGK...	246		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC28876
P42208-246-unknown	IEAKGK...	246		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29943
P42208-262-unknown	VVEVEN...	262		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33556
P42208-266-unmodified	ENPEHN...	266			N-TAILS		Overall CM.	Prudova A.: Multiplex N-terminome analysis of MMP-2 and MMP-9...	20305284

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...QQPTQF	8	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33554
...EKIERT	77	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000114614
...KTIISY	120	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000115536
...DNRVHC	147	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000118621
...DNRVHC	147	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000121974
...VNIVPV	179	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33555
...IKIYHL	212	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000120694
...KIYHLP	213	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000120511
...ESDEDE	221	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000108534
...ESDEDE	221	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000117517
...SIPFSV	238	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34625
...GSNQLI	245	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28876
...GSNQLI	245	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29943
...LYPWGV	261	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33556
...LGQHV	361	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MMP2_MOUSE	8	PTQF.\|.FINP	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
MMP2_MOUSE	179	IVPV.\|.VIAK	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
MMP9_MOUSE	238	PFSV.\|.VVGS	inferred from experiment	unknown	MEROPS	Overall CM	Prudova A et al.:Multiplex N-terminome analysis ... (M10.004)	20305284,
CATD_MOUSE	245	NQLI.\|.IEAK	inferred from experiment	unknown	MEROPS		Merops CATD_MOUSE -> SEPT2_MOUSE @245
CATE_MOUSE	245	NQLI.\|.IEAK	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> SEPT2_MOUSE @245
MMP2_MOUSE	261	PWGV.\|.VVEV	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)