P42932: T-complex protein 1 subunit theta

General Information

Protein names	- T-complex protein 1 subunit theta - TCP-1-theta - CCT-theta
Gene names	Cct8
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	P42932

10 N-termini

8 C-termini

5 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MALHVPKAPG FAQMLKDGAK HFSGLEEAVY RNIQACKELA QTTRTAYGPN GMNKMVINRL
        70         80         90        100        110        120
EKLFVTNDAA TILRELEVQH PAAKMIVMAS HMQEQEVGDG TNFVLVFAGA LLELAEELLR
       130        140        150        160        170        180
IGLSVSEVIS GYEIACKKAH EILPELVCCS AKNLRDVDEV SSLLRTSIMS KQYGSETFLA
       190        200        210        220        230        240
KLIAQACVSI FPDSGNFNVD NIRVCKILGS GIYSSSVLHG MVFKKETEGD VTSVKDAKIA
       250        260        270        280        290        300
VYSCPFDGMI TETKGTVLIK TAEELMNFSK GEENLMDAQV KAIAGTGANV IVTGGKVADI
       310        320        330        340        350        360
ALHYANKYNI MLVRLNSKWD LRRLCKTVGA TALPKLTPPV QEEMGHCDSV YLSEVGDTQV
       370        380        390        400        410        420
VVFKHEKEDG AISTIVLRGS TDNLMDDIER AVDDGVNTFK VLTRDKRLVP GGGATEIELA
       430        440        450        460        470        480
KQITSYGETC PGLEQYAIKK FAEAFEAIPR ALAENSGVKA NEVISKLYSV HQEGNKNVGL
       490        500        510        520        530        540
DIEAEVPAVK DMLEASILDT YLGKYWAIKL ATNAAVTVLR VDQIIMAKPA GGPKPPSGKK

DWDDDQND

Isoforms

Sequence View

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Evidence Codes:

Methodology:

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Protease Assignment Confidence:

Evidence Names:

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Protein Neighborhood

Domains & Features

10 N-termini - 8 C-termini - 5 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P42932-2-unknown	MALHVP...	1		inferred from similarity	unknown	UniProtKB		inferred from uniprot (by similarity)
P42932-2-unknown	MALHVP...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P42932-2-Acetylation	ALHVPK...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P42932-2-Acetylation	ALHVPK...	2	acetylation-	inferred from similarity	unknown	UniProtKB		inferred from uniprot (by similarity)
P42932-15-unknown	LKDGAK...	15		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33557
P42932-16-unmodified	KDGAKH...	16			N-TAILS		Overall CM.	Prudova A.: Multiplex N-terminome analysis of MMP-2 and MMP-9...	20305284
P42932-17-unknown	DGAKHF...	17			N-TAILS		Overall CM.	auf dem Keller U.: A statistics-based platform for quantitative N-terminome...	20305283
P42932-22-unknown	FSGLEE...	22		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33558
P42932-37-unknown	KELAQT...	37		inferred from electronic annotation	unknown	TISdb		inferred from TISdb
P42932-55-unknown	MVINRL...	55		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSMUSP00000135377
P42932-55-unknown	MVINRL...	55		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSMUSP00000135830
P42932-64-unknown	FVTNDA...	64		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC28877
P42932-64-unknown	FVTNDA...	64		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29945
P42932-511-unknown	ATNAAV...	511		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29946

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...GFAQML	14	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33557
...DGAKHF	21	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33558
...RLEKLF	63	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28877
...RLEKLF	63	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29945
...LIAQAC	186	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000135830
...LGSGIY	212	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000135377
...EAEVPA	487	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000134920
...WAIKLA	510	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29946
...DDQND	548	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MMP2_MOUSE	14	AQML.\|.LKDG	inferred from experiment	unknown	MEROPS	Overall CM	Prudova A et al.:Multiplex N-terminome analysis ... (M10.004)	20305284,
MMP2_MOUSE	21	AKHF.\|.FSGL	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
CATD_MOUSE	63	EKLF.\|.FVTN	inferred from experiment	unknown	MEROPS		Merops CATD_MOUSE -> TCPQ_MOUSE @63
CATE_MOUSE	63	EKLF.\|.FVTN	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> TCPQ_MOUSE @63
CATE_MOUSE	510	IKLA.\|.ATNA	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> TCPQ_MOUSE @510

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)