P46782: 40S ribosomal protein S5

General Information

Protein names	- 40S ribosomal protein S5 - Small ribosomal subunit protein uS7 {ECO:0000303\|PubMed:24524803} - 40S ribosomal protein S5, N-terminally processed
Gene names	RPS5
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P46782

13 N-termini

3 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MTEWETAAPA VAETPDIKLF GKWSTDDVQI NDISLQDYIA VKEKYAKYLP HSAGRYAAKR
        70         80         90        100        110        120
FRKAQCPIVE RLTNSMMMHG RNNGKKLMTV RIVKHAFEII HLLTGENPLQ VLVNAIINSG
       130        140        150        160        170        180
PREDSTRIGR AGTVRRQAVD VSPLRRVNQA IWLLCTGARE AAFRNIKTIA ECLADELINA
       190        200
AKGSSNSYAI KKKDELERVA KSNR

Isoforms

Sequence View

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Methodology:

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Protease Assignment Confidence:

Evidence Names:

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Lab:

Protein Neighborhood

Domains & Features

13 N-termini - 3 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P46782-1-Acetylation	MTEWET...	1	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P46782-1-Acetylation	MTEWET...	1	acetylation-		other		CNRS/ISV	Large_scale_NTA_Human
P46782-2-Acetylation	TEWETA...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P46782-2-Acetylation	TEWETA...	2	acetylation-		other		CNRS/ISV	Large_scale_NTA_Human
P46782-6-unknown	TAAPAV...	6		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC5888
P46782-6-	TAAPAV...	6			Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
P46782-7-	AAPAVA...	7			Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
P46782-10-	AVAETP...	10			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P46782-10-	AVAETP...	10			Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
P46782-10-	AVAETP...	10			Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
P46782-43-unknown	EKYAKY...	43			unknown			Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
P46782-43-	EKYAKY...	43			Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
P46782-45-unknown	YAKYLP...	45			unknown			Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
P46782-45-	YAKYLP...	45			Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
P46782-137-unknown	QAVDVS...	137			unknown			Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
P46782-137-	QAVDVS...	137			Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
P46782-187-	SYAIKK...	187			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
P46782-187-	SYAIKK...	187			Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...MTEWET	5	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC5888
...LERVAK	200	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000471185
...AKSNR	204	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATL1_HUMAN	5	EWET.\|.TAAP	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)