P47753: F-actin-capping protein subunit alpha-1

General Information

Protein names	- F-actin-capping protein subunit alpha-1 - CapZ alpha-1
Gene names	Capza1
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	P47753

8 N-termini

5 C-termini

6 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MADFEDRVSD EEKVRIAAKF ITHAPPGEFN EVFNDVRLLL NNDNLLREGA AHAFAQYNMD
        70         80         90        100        110        120
QFTPVKIEGY DDQVLITEHG DLGNSRFLDP RNQISFKFDH LRKEASDPQP EDVDGGLKSW
       130        140        150        160        170        180
RESCDSALRA YVKDHYSNGF CTVYAKTIDG QQTIIACIES HQFQPKNFWN GRWRSEWKFT
       190        200        210        220        230        240
ITPPSAQVVG VLKIQVHYYE DGNVQLVSHK DVQDSVTVSN EVQTTKEFIK IIESAENEYQ
       250        260        270        280
TAISENYQTM SDTTFKALRR QLPVTRTKID WNKILSYKIG KEMQNA

Isoforms

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

8 N-termini - 5 C-termini - 6 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P47753-2-unknown	MADFED...	1		inferred from similarity	unknown	UniProtKB		inferred from uniprot (by similarity)
P47753-2-unknown	MADFED...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P47753-2-Acetylation	ADFEDR...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P47753-2-Acetylation	ADFEDR...	2	acetylation-		N-TAILS		Overall CM.	Kleifeldt O. et al.: Isotopic labeling of terminal amines in complex samples identifies...	20208520
P47753-2-Acetylation	ADFEDR...	2	acetylation-	inferred from similarity	unknown	UniProtKB		inferred from uniprot (by similarity)
P47753-13-unknown	KVRIAA...	13		inferred from electronic annotation	unknown	TISdb		inferred from TISdb
P47753-20-unmodified	FITHAP...	20			N-TAILS		Overall CM.	Prudova A.: Multiplex N-terminome analysis of MMP-2 and MMP-9...	20305284
P47753-29-unknown	FNEVFN...	29		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33565
P47753-30-unknown	NEVFND...	30		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29975
P47753-30-unknown	NEVFND...	30		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33566
P47753-39-unknown	LLNNDN...	39		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33567
P47753-39-unknown	LLNNDN...	39		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC28884
P47753-67-unknown	IEGYDD...	67		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33568

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...APPGEF	28	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33565
...PPGEFN	29	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29975
...PPGEFN	29	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33566
...NDVRLL	38	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33567
...NDVRLL	38	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28884
...FTPVKI	66	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33568
...EMQNA	286	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MMP2_MOUSE	28	PGEF.\|.FNEV	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
CATE_MOUSE	29	GEFN.\|.NEVF	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> CAZA1_MOUSE @29
MMP2_MOUSE	29	GEFN.\|.NEVF	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
MMP2_MOUSE	38	VRLL.\|.LLNN	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
CATD_MOUSE	38	VRLL.\|.LLNN	inferred from experiment	unknown	MEROPS		Merops CATD_MOUSE -> CAZA1_MOUSE @38
MMP2_MOUSE	66	PVKI.\|.IEGY	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)