P47756: F-actin-capping protein subunit beta

General Information

Protein names	- F-actin-capping protein subunit beta - CapZ beta
Gene names	CAPZB
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P47756

7 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MSDQQLDCAL DLMRRLPPQQ IEKNLSDLID LVPSLCEDLL SSVDQPLKIA RDKVVGKDYL
        70         80         90        100        110        120
LCDYNRDGDS YRSPWSNKYD PPLEDGAMPS ARLRKLEVEA NNAFDQYRDL YFEGGVSSVY
       130        140        150        160        170        180
LWDLDHGFAG VILIKKAGDG SKKIKGCWDS IHVVEVQEKS SGRTAHYKLT STVMLWLQTN
       190        200        210        220        230        240
KSGSGTMNLG GSLTRQMEKD ETVSDCSPHI ANIGRLVEDM ENKIRSTLNE IYFGKTKDIV
       250        260        270
NGLRSIDAIP DNQKFKQLQR ELSQVLTQRQ IYIQPDN

Isoforms

- Isoform 2 of F-actin-capping protein subunit beta

Sequence View

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Evidence Codes:

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Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

7 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P47756-1-unknown	MSDQQL...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt69292
P47756-2-unknown	MSDQQL...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P47756-2-Acetylation	SDQQLD...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P47756-2-Acetylation	SDQQLD...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
P47756-2-Acetylation	SDQQLD...	2	acetylation-		other		CNRS/ISV	Large_scale_NTA_Human
P47756-2-Acetylation	SDQQLD...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
P47756-2-Acetylation	SDQQLD...	2	acetylation-		N-TAILS		Overall Laboratory	Lange_Huesgen_et_al-RBC
P47756-2-Acetylation	SDQQLD...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt110681
P47756-95-acetylation	KLEVEA...	95	acetylation-		N-TAILS		Overall Laboratory	Lange_Huesgen_et_al-RBC
P47756-95-acetylation	KLEVEA...	95	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt182728
P47756-150-	SIHVVE...	150			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P47756-150-	SIHVVE...	150			Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
P47756-150-unknown	SIHVVE...	150		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt171668
P47756-205-unknown	DCSPHI...	205		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC19125
P47756-205-unknown	DCSPHI...	205		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt146726

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...DETVSD	204	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC19125
...DETVSD	204	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt130038
...IQPDN	277	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MEP1B_HUMAN	204	TVSD.\|.DCSP	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)