TopFIND 4.0

P48428: Tubulin-specific chaperone A

General Information

Protein names	- Tubulin-specific chaperone A - TCP1-chaperonin cofactor A - Tubulin-folding cofactor A - CFA
Gene names	Tbca
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	P48428

6

N-termini

4

C-termini

4

Cleavages

0

Substrates

Sequence

10 20 30 40 50 60
MADPRVRQIK IKTGVVRRLV KERVMYEKEA KQQEEKIEKM KAEDGENYAI KKQAEILQES
70 80 90 100
RMMIPDCQRR LEAAYTDLQQ ILESEKDLEE AEEYKEARVV LDSVKLEA

Isoforms

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

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Biological System:

Protease Assignment Confidence:

Evidence Names:

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Lab:

Protein Neighborhood

Domains & Features

6 N-termini - 4 C-termini - 4 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P48428-2-unknown	MADPRV...	1		inferred from similarity	unknown	UniProtKB		inferred from uniprot (by similarity)
P48428-2-unknown	MADPRV...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P48428-2-Acetylation	ADPRVR...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P48428-2-Acetylation	ADPRVR...	2	acetylation-	inferred from similarity	unknown	UniProtKB		inferred from uniprot (by similarity)
P48428-70-unmodified	RLEAAY...	70			N-TAILS		Overall CM.	Kleifeldt O. et al.: Isotopic labeling of terminal amines in complex samples identifies...	20208520
P48428-79-unknown	QQILES...	79		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC28895
P48428-81-unknown	ILESEK...	81		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33581
P48428-89-unknown	EEAEEY...	89		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC30001
P48428-89-unknown	EEAEEY...	89		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC28896

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...AYTDLQ	78	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC28895
	...TDLQQI	80	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33581
	...SEKDLE	88	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC30001
	...SEKDLE	88	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC28896
	...VKLEA	108	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATD_MOUSE	78	TDLQ.\|.QQIL	inferred from experiment	unknown	MEROPS		Merops CATD_MOUSE -> TBCA_MOUSE @78
MMP2_MOUSE	80	LQQI.\|.ILES	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
CATE_MOUSE	88	KDLE.\|.EEAE	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> TBCA_MOUSE @88
CATD_MOUSE	88	KDLE.\|.EEAE	inferred from experiment	unknown	MEROPS		Merops CATD_MOUSE -> TBCA_MOUSE @88

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)