P49069: Calcium signal-modulating cyclophilin ligand

General Information

Protein names	- Calcium signal-modulating cyclophilin ligand - CAML
Gene names	CAMLG
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P49069

6 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MESMAVATDG GERPGVPAGS GLSASQRRAE LRRRKLLMNS EQRINRIMGF HRPGSGAEEE
        70         80         90        100        110        120
SQTKSKQQDS DKLNSLSVPS VSKRVVLGDS VSTGTTDQQG GVAEVKGTQL GDKLDSFIKP
       130        140        150        160        170        180
PECSSDVNLE LRQRNRGDLT ADSVQRGSRH GLEQYLSRFE EAMKLRKQLI SEKPSQEDGN
       190        200        210        220        230        240
TTEEFDSFRI FRLVGCALLA LGVRAFVCKY LSIFAPFLTL QLAYMGLYKY FPKSEKKIKT
       250        260        270        280        290
TVLTAALLLS GIPAEVINRS MDTYSKMGEV FTDLCVYFFT FIFCHELLDY WGSEVP

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

6 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P49069-1-unknown	MESMAV...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P49069-5-	AVATDG...	5		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
P49069-10-	GGERPG...	10		Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
P49069-10-	GGERPG...	10		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
P49069-10-	GGERPG...	10		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_Etoposide	23264352
P49069-10-	GGERPG...	10		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P49069-10-	GGERPG...	10		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
P49069-10-	GGERPG...	10		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
P49069-10-	GGERPG...	10		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
P49069-10-unknown	GGERPG...	10		unknown			Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
P49069-52-unknown	RPGSGA...	52	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC5904
P49069-116-unknown	SFIKPP...	116		unknown			Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...IMGFHR	51	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC5904
	...GSEVP	296	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATL1_HUMAN	51	GFHR.\|.RPGS	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)