TopFIND 4.0

P49189: 4-trimethylaminobutyraldehyde dehydrogenase

General Information

Protein names
- 4-trimethylaminobutyraldehyde dehydrogenase
- TMABA-DH {ECO:0000303|PubMed:10702312}
- TMABALDH {ECO:0000303|PubMed:30914451}
- 1.2.1.47 {ECO:0000269|PubMed:10702312, ECO:0000269|PubMed:30914451, ECO:0000269|PubMed:8645224}
- Aldehyde dehydrogenase E3 isozyme {ECO:0000303|PubMed:8645224}
- Aldehyde dehydrogenase family 9 member A1
- 1.2.1.3 {ECO:0000269|PubMed:10702312, ECO:0000269|PubMed:30914451, ECO:0000269|PubMed:8645224}
- Gamma-aminobutyraldehyde dehydrogenase {ECO:0000303|PubMed:10702312}
- 1.2.1.19 {ECO:0000269|PubMed:10702312, ECO:0000269|PubMed:30914451, ECO:0000269|PubMed:8645224}
- R-aminobutyraldehyde dehydrogenase
- 4-trimethylaminobutyraldehyde dehydrogenase, N-terminally processed
Gene names ALDH9A1
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID P49189

8

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MSTGTFVVSQ PLNYRGGARV EPADASGTEK AFEPATGRVI ATFTCSGEKE VNLAVQNAKA 
        70         80         90        100        110        120 
AFKIWSQKSG MERCRILLEA ARIIREREDE IATMECINNG KSIFEARLDI DISWQCLEYY 
       130        140        150        160        170        180 
AGLAASMAGE HIQLPGGSFG YTRREPLGVC VGIGAWNYPF QIASWKSAPA LACGNAMVFK 
       190        200        210        220        230        240 
PSPFTPVSAL LLAEIYSEAG VPPGLFNVVQ GGAATGQFLC QHPDVAKVSF TGSVPTGMKI 
       250        260        270        280        290        300 
MEMSAKGIKP VTLELGGKSP LIIFSDCDMN NAVKGALMAN FLTQGQVCCN GTRVFVQKEI 
       310        320        330        340        350        360 
LDKFTEEVVK QTQRIKIGDP LLEDTRMGPL INRPHLERVL GFVKVAKEQG AKVLCGGDIY 
       370        380        390        400        410        420 
VPEDPKLKDG YYMRPCVLTN CRDDMTCVKE EIFGPVMSIL SFDTEAEVLE RANDTTFGLA 
       430        440        450        460        470        480 
AGVFTRDIQR AHRVVAELQA GTCFINNYNV SPVELPFGGY KKSGFGRENG RVTIEYYSQL 
       490    
KTVCVEMGDV ESAF

Isoforms

- Isoform 2 of 4-trimethylaminobutyraldehyde dehydrogenase - Isoform 3 of 4-trimethylaminobutyraldehyde dehydrogenase

Sequence View

        10         20         30         40         50         60 
MSTGTFVVSQ PLNYRGGARV EPADASGTEK AFEPATGRVI ATFTCSGEKE VNLAVQNAKA 
        70         80         90        100        110        120 
AFKIWSQKSG MERCRILLEA ARIIREREDE IATMECINNG KSIFEARLDI DISWQCLEYY 
       130        140        150        160        170        180 
AGLAASMAGE HIQLPGGSFG YTRREPLGVC VGIGAWNYPF QIASWKSAPA LACGNAMVFK 
       190        200        210        220        230        240 
PSPFTPVSAL LLAEIYSEAG VPPGLFNVVQ GGAATGQFLC QHPDVAKVSF TGSVPTGMKI 
       250        260        270        280        290        300 
MEMSAKGIKP VTLELGGKSP LIIFSDCDMN NAVKGALMAN FLTQGQVCCN GTRVFVQKEI 
       310        320        330        340        350        360 
LDKFTEEVVK QTQRIKIGDP LLEDTRMGPL INRPHLERVL GFVKVAKEQG AKVLCGGDIY 
       370        380        390        400        410        420 
VPEDPKLKDG YYMRPCVLTN CRDDMTCVKE EIFGPVMSIL SFDTEAEVLE RANDTTFGLA 
       430        440        450        460        470        480 
AGVFTRDIQR AHRVVAELQA GTCFINNYNV SPVELPFGGY KKSGFGRENG RVTIEYYSQL 
       490    
KTVCVEMGDV ESAF         10         20         30         40         50         60 
MSTGTFVVSQ PLNYRGGARV EPADASGTEK AFEPATGRVI ATFTCSGEKE VNLAVQNAKA 
        70         80         90        100        110        120 
AFKIWSQKSG MERCRILLEA ARIIREREDE IATMECINNG KSIFEARLDI DISWQCLEYY 
       130        140        150        160        170        180 
AGLAASMAGE HIQLPGGSFG YTRREPLGVC VGIGAWNYPF QIASWKSAPA LACGNAMVFK 
       190        200        210        220        230        240 
PSPFTPVSAL LLAEIYSEAG VPPGLFNVVQ GGAATGQFLC QHPDVAKVSF TGSVPTGMKI 
       250        260        270        280        290        300 
MEMSAKGIKP VTLELGGKSP LIIFSDCDMN NAVKGALMAN FLTQGQVCCN GTRVFVQKEI 
       310        320        330        340        350        360 
LDKFTEEVVK QTQRIKIGDP LLEDTRMGPL INRPHLERVL GFVKVAKEQG AKVLCGGDIY 
       370        380        390        400        410        420 
VPEDPKLKDG YYMRPCVLTN CRDDMTCVKE EIFGPVMSIL SFDTEAEVLE RANDTTFGLA 
       430        440        450        460        470        480 
AGVFTRDIQR AHRVVAELQA GTCFINNYNV SPVELPFGGY KKSGFGRENG RVTIEYYSQL 
       490    
KTVCVEMGDV ESAF



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Protein Neighborhood

Domains & Features

8 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...VESAF 494 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)