P62259: 14-3-3 protein epsilon

General Information

Protein names	- 14-3-3 protein epsilon - 14-3-3E
Gene names	Ywhae
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	P62259

14 N-termini

14 C-termini

12 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MDDREDLVYQ AKLAEQAERY DEMVESMKKV AGMDVELTVE ERNLLSVAYK NVIGARRASW
        70         80         90        100        110        120
RIISSIEQKE ENKGGEDKLK MIREYRQMVE TELKLICCDI LDVLDKHLIP AANTGESKVF
       130        140        150        160        170        180
YYKMKGDYHR YLAEFATGND RKEAAENSLV AYKAASDIAM TELPPTHPIR LGLALNFSVF
       190        200        210        220        230        240
YYEILNSPDR ACRLAKAAFD DAIAELDTLS EESYKDSTLI MQLLRDNLTL WTSDMQGDGE
       250
EQNKEALQDV EDENQ

Isoforms

Sequence View

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Evidence Codes:

Methodology:

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Protease Assignment Confidence:

Evidence Names:

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Lab:

Protein Neighborhood

Domains & Features

14 N-termini - 14 C-termini - 12 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P62259-1-Acetylation	MDDRED...	1	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P62259-1-Acetylation	MDDRED...	1	acetylation-		N-TAILS		Overall CM.	auf dem Keller U.: A statistics-based platform for quantitative N-terminome...	20305283
P62259-1-Acetylation	MDDRED...	1	acetylation-		N-TAILS		Overall CM.	Kleifeldt O. et al.: Isotopic labeling of terminal amines in complex samples identifies...	20208520
P62259-1-Acetylation	MDDRED...	1	acetylation-		unknown			Kleifeldt O. et al.: N-terminome analysis of bronchoalveolar lavage fluids collected from...	20208520
P62259-1-Acetylation	MDDRED...	1	acetylation-		N-TAILS		Overall CM.	Prudova A.: Multiplex N-terminome analysis of MMP-2 and MMP-9...	20305284
P62259-5-acetylation	EDLVYQ...	5	acetylation-		N-TAILS		Overall CM.	auf dem Keller U.: A statistics-based platform for quantitative N-terminome...	20305283
P62259-5-acetylation	EDLVYQ...	5	acetylation-		N-TAILS		Overall CM.	Prudova A.: Multiplex N-terminome analysis of MMP-2 and MMP-9...	20305284
P62259-7-unknown	LVYQAK...	7		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33678
P62259-8-unknown	VYQAKL...	8		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC30173
P62259-10-unknown	QAKLAE...	10		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC30174
P62259-27-unknown	MKKVAG...	27		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33679
P62259-33-unknown	MDVELT...	33		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33680
P62259-44-unknown	LLSVAY...	44		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33681
P62259-152-unknown	YKAASD...	152		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33682
P62259-153-unknown	KAASDI...	153		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33683
P62259-158-unknown	IAMTEL...	158		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33684
P62259-178-unknown	SVFYYE...	178		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC30175
P62259-179-unknown	VFYYEI...	179		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33685
P62259-181-unknown	YYEILN...	181		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC30176

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...DDREDL	6	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33678
...DREDLV	7	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30173
...EDLVYQ	9	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30174
...EMVESM	26	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33679
...KKVAGM	32	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33680
...VEERNL	43	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33681
...GNDRKE	142	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000123504
...NSLVAY	151	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33682
...SLVAYK	152	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33683
...KAASDI	157	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33684
...LALNFS	177	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30175
...ALNFSV	178	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33685
...NFSVFY	180	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30176
...EDENQ	255	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MMP2_MOUSE	6	REDL.\|.LVYQ	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
CATE_MOUSE	7	EDLV.\|.VYQA	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> 1433E_MOUSE @7
CATE_MOUSE	9	LVYQ.\|.QAKL	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> 1433E_MOUSE @9
MMP2_MOUSE	26	VESM.\|.MKKV	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
MMP2_MOUSE	32	VAGM.\|.MDVE	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
MMP2_MOUSE	43	ERNL.\|.LLSV	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
MMP2_MOUSE	151	LVAY.\|.YKAA	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
MMP2_MOUSE	152	VAYK.\|.KAAS	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
MMP2_MOUSE	157	ASDI.\|.IAMT	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
CATE_MOUSE	177	LNFS.\|.SVFY	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> 1433E_MOUSE @177
MMP2_MOUSE	178	NFSV.\|.VFYY	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
CATE_MOUSE	180	SVFY.\|.YYEI	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> 1433E_MOUSE @180

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)