P70195: Proteasome subunit beta type-7

General Information

Protein names	- Proteasome subunit beta type-7 - 3.4.25.1 - Macropain chain Z - Multicatalytic endopeptidase complex chain Z - Proteasome subunit Z
Gene names	Psmb7
Organism	Mus musculus
Protease Family	T01.011
Protease ID	T01.011
Chromosome location
UniProt ID	P70195

4 N-termini

3 C-termini

2 Cleavages

1 Substrates

Sequence

        10         20         30         40         50         60
MAAVSVFQPP VGGFSFDNCR RNAVLEADFA KKGFKLPKAR KTGTTIAGVV YKDGIVLGAD
        70         80         90        100        110        120
TRATEGMVVA DKNCSKIHFI SPNIYCCGAG TAADTDMTTQ LISSNLELHS LTTGRLPRVV
       130        140        150        160        170        180
TANRMLKQML FRYQGYIGAA LVLGGVDVTG PHLYSIYPHG STDKLPYVTM GSGSLAAMAV
       190        200        210        220        230        240
FEDKFRPDME EEEAKKLVSE AIAAGIFNDL GSGSNIDLCV ISKSKLDFLR PFSVPNKKGT
       250        260        270
RLGRYRCEKG TTAVLTEKVT PLEIEVLEET VQTMDTS

Isoforms

Sequence View

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

4 N-termini - 3 C-termini - 2 Cleavages - 1 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P70195-44-unmodified	TTIAGV...	44		N-TAILS		Overall CM.	Kleifeldt O. et al.: Isotopic labeling of terminal amines in complex samples identifies...	20208520
P70195-44-unmodified	TTIAGV...	44		unknown			Kleifeldt O. et al.: N-terminome analysis of bronchoalveolar lavage fluids collected from...	20208520
P70195-44-unknown	TTIAGV...	44	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P70195-44-unknown	TTIAGV...	44		N-TAILS		Overall CM.	auf dem Keller U.: A statistics-based platform for quantitative N-terminome...	20305283
P70195-44-unknown	TTIAGV...	44	inferred from similarity	unknown	UniProtKB		inferred from uniprot (by similarity)
P70195-49-unknown	VVYKDG...	49	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33790
P70195-53-unknown	DGIVLG...	53	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33791

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...TTIAGV	48	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33790
...GVVYKD	52	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33791
...TMDTS	277	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MMP2_MOUSE	48	IAGV.\|.VVYK	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
MMP2_MOUSE	52	VYKD.\|.DGIV	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
JAK1_MOUSE	374	ITHI.\|.IVIK	inferred from experiment	unknown	MEROPS	Schild H	Dick TP et al.:Contribution of proteasomal bet... (T01.011)	9748229,