P80314: T-complex protein 1 subunit beta

General Information

Protein names	- T-complex protein 1 subunit beta - TCP-1-beta - CCT-beta
Gene names	Cct2
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	P80314

10 N-termini

5 C-termini

4 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MASLSLAPVN IFKAGADEER AETARLSSFI GAIAIGDLVK STLGPKGMDK ILLSSGRDAA
        70         80         90        100        110        120
LMVTNDGATI LKNIGVDNPA AKVLVDMSRV QDDEVGDGTT SVTVLAAELL REAESLIAKK
       130        140        150        160        170        180
IHPQTIISGW REATKAAREA LLSSAVDHGS DEARFWQDLM NIAGTTLSSK LLTHHKDHFT
       190        200        210        220        230        240
KLAVEAVLRL KGSGNLEAIH VIKKLGGSLA DSYLDEGFLL DKKIGVNQPK RIENAKILIA
       250        260        270        280        290        300
NTGMDTDKIK IFGSRVRVDS TAKVAEIEHA EKEKMKEKVE RILKHGINCF INRQLIYNYP
       310        320        330        340        350        360
EQLFGAAGVM AIEHADFAGV ERLALVTGGE IASTFDHPEL VKLGSCKLIE EVMIGEDKLI
       370        380        390        400        410        420
HFSGVALGEA CTIVLRGATQ QILDEAERSL HDALCVLAQT VKDPRTVYGG GCSEMLMAHA
       430        440        450        460        470        480
VTQLANRTPG KEAVAMESFA KALRMLPTII ADNAGYDSAD LVAQLRAAHS EGHITAGLDM
       490        500        510        520        530
KEGTIGDMAV LGITESFQVK RQVLLSAAEA AEVILRVDNI IKAAPRKRVP DHHPC

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

10 N-termini - 5 C-termini - 4 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P80314-2-unknown	MASLSL...	1		inferred from similarity	unknown	UniProtKB		inferred from uniprot (by similarity)
P80314-2-unknown	MASLSL...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P80314-2-Acetylation	ASLSLA...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P80314-2-Acetylation	ASLSLA...	2	acetylation-		unknown			Kleifeldt O. et al.: N-terminome analysis of bronchoalveolar lavage fluids collected from...	20208520
P80314-2-Acetylation	ASLSLA...	2	acetylation-	inferred from similarity	unknown	UniProtKB		inferred from uniprot (by similarity)
P80314-11-unknown	IFKAGA...	11		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33811
P80314-73-unknown	NIGVDN...	73			N-TAILS		Overall CM.	auf dem Keller U.: A statistics-based platform for quantitative N-terminome...	20305283
P80314-74-unknown	IGVDNP...	74		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33812
P80314-158-unknown	DLMNIA...	158		inferred from electronic annotation	unknown	TISdb		inferred from TISdb
P80314-169-unknown	SKLLTH...	169		inferred from electronic annotation	unknown	TISdb		inferred from TISdb
P80314-218-unknown	FLLDKK...	218		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29082
P80314-219-unknown	LLDKKI...	219		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC30336
P80314-282-unmodified	ILKHGI...	282			N-TAILS		Overall CM.	Prudova A.: Multiplex N-terminome analysis of MMP-2 and MMP-9...	20305284

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...LAPVNI	10	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33811
...TILKNI	73	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33812
...YLDEGF	217	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29082
...LDEGFL	218	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30336
...DHHPC	535	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MMP2_MOUSE	10	PVNI.\|.IFKA	inferred from experiment	unknown	MEROPS	Overall CM	Prudova A et al.:Multiplex N-terminome analysis ... (M10.004)	20305284,
MMP2_MOUSE	73	LKNI.\|.IGVD	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
CATD_MOUSE	217	DEGF.\|.FLLD	inferred from experiment	unknown	MEROPS		Merops CATD_MOUSE -> TCPB_MOUSE @217
CATE_MOUSE	218	EGFL.\|.LLDK	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> TCPB_MOUSE @218

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)