P80316: T-complex protein 1 subunit epsilon

General Information

Protein names	- T-complex protein 1 subunit epsilon - TCP-1-epsilon - CCT-epsilon
Gene names	Cct5
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	P80316

13 N-termini

10 C-termini

12 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MASVGTLAFD EYGRPFLIIK DQDRKSRLMG LEALKSHIMA AKAVANTMRT SLGPNGLDKM
        70         80         90        100        110        120
MVDKDGDVTI TNDGATILSM MDVDHQIAKL MVELSKSQDD EIGDGTTGVV VLAGALLEEA
       130        140        150        160        170        180
EQLLDRGIHP IRIADGYEQA ARIAIQHLDK ISDKVLVDIN NPEPLIQTAK TTLGSKVINS
       190        200        210        220        230        240
CHRQMAEIAV NAVLTVADME RRDVDFELIK VEGKVGGRLE DTKLIKGVIV DKDFSHPQMP
       250        260        270        280        290        300
KKVVDAKIAI LTCPFEPPKP KTKHKLDVMS VEDYKALQKY EKEKFEEMIK QIKETGANLA
       310        320        330        340        350        360
ICQWGFDDEA NHLLLQNGLP AVRWVGGPEI ELIAIATGGR IVPRFSELTS EKLGFAGVVQ
       370        380        390        400        410        420
EISFGTTKDK MLVIEKCKNS RAVTIFIRGG NKMIIEEAKR SLHDALCVIR NLIRDNRVVY
       430        440        450        460        470        480
GGGAAEISCA LAVSQEADKC PTLEQYAMRA FADALEVIPM ALSENSGMNP IQTMTEVRAR
       490        500        510        520        530        540
QVKESNPALG IDCLHKGSND MQYQHVIETL IGKKQQISLA TQMVRMILKI DDIRKPGESE

E

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

13 N-termini - 10 C-termini - 12 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P80316-2-unknown	MASVGT...	1		inferred from similarity	unknown	UniProtKB		inferred from uniprot (by similarity)
P80316-2-unknown	MASVGT...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P80316-2-Acetylation	ASVGTL...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P80316-2-Acetylation	ASVGTL...	2	acetylation-		N-TAILS		Overall CM.	Kleifeldt O. et al.: Isotopic labeling of terminal amines in complex samples identifies...	20208520
P80316-2-Acetylation	ASVGTL...	2	acetylation-	inferred from similarity	unknown	UniProtKB		inferred from uniprot (by similarity)
P80316-17-unknown	LIIKDQ...	17		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC30338
P80316-17-unknown	LIIKDQ...	17		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29084
P80316-23-unknown	DRKSRL...	23		inferred from electronic annotation	unknown	TISdb		inferred from TISdb
P80316-39-unknown	MAAKAV...	39		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSMUSP00000125566
P80316-40-unknown	AAKAVA...	40		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC30339
P80316-133-unknown	IADGYE...	133		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33815
P80316-133-unknown	IADGYE...	133		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC30340
P80316-171-unmodified	TTLGSK...	171			N-TAILS		Overall CM.	Prudova A.: Multiplex N-terminome analysis of MMP-2 and MMP-9...	20305284
P80316-193-unknown	VLTVAD...	193		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC30341
P80316-207-unknown	ELIKVE...	207		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC30342
P80316-209-unknown	IKVEGK...	209		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC30343
P80316-511-unknown	IGKKQQ...	511		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC30344
P80316-511-unknown	IGKKQQ...	511		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29085
P80316-527-unknown	ILKIDD...	527		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC30345
P80316-527-unknown	ILKIDD...	527		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29086

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...YGRPFL	16	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30338
...YGRPFL	16	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29084
...KSHIMA	39	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30339
...IHPIRI	132	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33815
...IHPIRI	132	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30340
...IAVNAV	192	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30341
...RDVDFE	206	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30342
...VDFELI	208	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30343
...DFSHPQ	237	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000125566
...VIETLI	510	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30344
...VIETLI	510	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29085
...QMVRMI	526	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30345
...QMVRMI	526	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29086
...GESEE	541	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATE_MOUSE	16	RPFL.\|.LIIK	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> TCPE_MOUSE @16
CATD_MOUSE	16	RPFL.\|.LIIK	inferred from experiment	unknown	MEROPS		Merops CATD_MOUSE -> TCPE_MOUSE @16
CATE_MOUSE	39	HIMA.\|.AAKA	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> TCPE_MOUSE @39
MMP2_MOUSE	132	PIRI.\|.IADG	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
CATE_MOUSE	132	PIRI.\|.IADG	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> TCPE_MOUSE @132
CATE_MOUSE	192	VNAV.\|.VLTV	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> TCPE_MOUSE @192
CATE_MOUSE	206	VDFE.\|.ELIK	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> TCPE_MOUSE @206
CATE_MOUSE	208	FELI.\|.IKVE	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> TCPE_MOUSE @208
CATE_MOUSE	510	ETLI.\|.IGKK	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> TCPE_MOUSE @510
CATD_MOUSE	510	ETLI.\|.IGKK	inferred from experiment	unknown	MEROPS		Merops CATD_MOUSE -> TCPE_MOUSE @510
CATE_MOUSE	526	VRMI.\|.ILKI	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> TCPE_MOUSE @526
CATD_MOUSE	526	VRMI.\|.ILKI	inferred from experiment	unknown	MEROPS		Merops CATD_MOUSE -> TCPE_MOUSE @526

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)