P80318: T-complex protein 1 subunit gamma

General Information

Protein names	- T-complex protein 1 subunit gamma - TCP-1-gamma - CCT-gamma - Matricin - mTRiC-P5
Gene names	Cct3
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	P80318

18 N-termini

10 C-termini

8 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MMGHRPVLVL SQNTKRESGR KVQSGNINAA KTIADIIRTC LGPKSMMKML LDPMGGIVMT
        70         80         90        100        110        120
NDGNAILREI QVQHPAAKSM IEISRTQDEE VGDGTTSVII LAGEMLSVAE HFLEQQMHPT
       130        140        150        160        170        180
VVISAYRMAL DDMISTLKKI STPVDVNNRE MMLSIINSSI TTKVISRWSS LACNIALDAV
       190        200        210        220        230        240
KTVQFEENGR KEIDIKKYAR VEKIPGGIIE DSCVLRGVMI NKDVTHPRMR RYIKNPRIVL
       250        260        270        280        290        300
LDSSLEYKKG ESQTDIEITR EEDFTRILQM EEEYIHQLCE DIIQLKPDVV ITEKGISDLA
       310        320        330        340        350        360
QHYLMRANVT AIRRVRKTDN NRIARACGAR IVSRPEELRE DDVGTGAGLL EIKKIGDEYF
       370        380        390        400        410        420
TFITDCKDPK ACTILLRGAS KEILSEVERN LQDAMQVCRN VLLDPQLVPG GGASEMAVAH
       430        440        450        460        470        480
ALTEKSKAMT GVEQWPYRAV AQALEVIPRT LIQNCGASTI RLLTSLRAKH TQESCETWGV
       490        500        510        520        530        540
NGETGTLVDM KELGIWEPLA VKLQTYKTAV ETAVLLLRID DIVSGHKKKG DDQNRQTGAP

DAGQE

Isoforms

Sequence View

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Evidence Codes:

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Protease Assignment Confidence:

Evidence Names:

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Protein Neighborhood

Domains & Features

18 N-termini - 10 C-termini - 8 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P80318-1-Acetylation	MMGHRP...	1	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P80318-1-Acetylation	MMGHRP...	1	acetylation-		N-TAILS		Overall CM.	Kleifeldt O. et al.: Isotopic labeling of terminal amines in complex samples identifies...	20208520
P80318-3-unknown	GHRPVL...	3			N-TAILS		Overall CM.	auf dem Keller U.: A statistics-based platform for quantitative N-terminome...	20305283
P80318-9-unknown	VLSQNT...	9		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC30348
P80318-21-unknown	KVQSGN...	21			N-TAILS		Overall CM.	auf dem Keller U.: A statistics-based platform for quantitative N-terminome...	20305283
P80318-27-unknown	INAAKT...	27		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33819
P80318-50-unknown	LLDPMG...	50		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC30349
P80318-78-unknown	KSMIEI...	78		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33820
P80318-139-unmodified	KISTPV...	139			N-TAILS		Overall CM.	Prudova A.: Multiplex N-terminome analysis of MMP-2 and MMP-9...	20305284
P80318-178-unknown	DAVKTV...	178		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC30350
P80318-201-unmodified	VEKIPG...	201			N-TAILS		Overall CM.	Prudova A.: Multiplex N-terminome analysis of MMP-2 and MMP-9...	20305284
P80318-378-unmodified	GASKEI...	378			N-TAILS		Overall CM.	Prudova A.: Multiplex N-terminome analysis of MMP-2 and MMP-9...	20305284
P80318-422-unknown	LTEKSK...	422		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33821
P80318-426-unmodified	SKAMTG...	426			N-TAILS		Overall CM.	Prudova A.: Multiplex N-terminome analysis of MMP-2 and MMP-9...	20305284
P80318-428-unmodified	AMTGVE...	428			N-TAILS		Overall CM.	Prudova A.: Multiplex N-terminome analysis of MMP-2 and MMP-9...	20305284
P80318-428-unknown	AMTGVE...	428			N-TAILS		Overall CM.	auf dem Keller U.: A statistics-based platform for quantitative N-terminome...	20305283
P80318-429-unknown	MTGVEQ...	429		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33822
P80318-439-unknown	AVAQAL...	439			N-TAILS		Overall CM.	auf dem Keller U.: A statistics-based platform for quantitative N-terminome...	20305283
P80318-506-unknown	YKTAVE...	506		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33823

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...HRPVLV	8	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30348
...VQSGNI	26	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33819
...SMMKML	49	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30349
...QHPAAK	77	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33820
...CNIALD	177	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30350
...AVAHAL	421	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33821
...EKSKAM	428	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33822
...LEVIPR	448	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000130616
...VKLQTY	505	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33823
...DAGQE	545	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATE_MOUSE	8	PVLV.\|.VLSQ	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> TCPG_MOUSE @8
MMP2_MOUSE	26	SGNI.\|.INAA	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
CATE_MOUSE	49	MKML.\|.LLDP	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> TCPG_MOUSE @49
MMP2_MOUSE	77	PAAK.\|.KSMI	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
CATE_MOUSE	177	IALD.\|.DAVK	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> TCPG_MOUSE @177
MMP2_MOUSE	421	AHAL.\|.LTEK	inferred from experiment	unknown	MEROPS	Overall CM	Prudova A et al.:Multiplex N-terminome analysis ... (M10.004)	20305284,
MMP2_MOUSE	428	SKAM.\|.MTGV	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
MMP2_MOUSE	505	LQTY.\|.YKTA	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)