Q13445: Transmembrane emp24 domain-containing protein 1

General Information

Protein names	- Transmembrane emp24 domain-containing protein 1 - Interleukin-1 receptor-like 1 ligand - Putative T1/ST2 receptor-binding protein - p24 family protein gamma-1 - Tp24 - p24gamma1
Gene names	TMED1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q13445

3 N-termini

2 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MMAAGAALAL ALWLLMPPVE VGGAGPPPIQ DGEFTFLLPA GRKQCFYQSA PANASLETEY
        70         80         90        100        110        120
QVIGGAGLDV DFTLESPQGV LLVSESRKAD GVHTVEPTEA GDYKLCFDNS FSTISEKLVF
       130        140        150        160        170        180
FELIFDSLQD DEEVEGWAEA VEPEEMLDVK MEDIKESIET MRTRLERSIQ MLTLLRAFEA
       190        200        210        220
RDRNLQEGNL ERVNFWSAVN VAVLLLVAVL QVCTLKRFFQ DKRPVPT

Isoforms

Sequence View

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(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

3 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q13445-24-	AGPPPI...	24		Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
Q13445-24-	AGPPPI...	24		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
Q13445-24-	AGPPPI...	24		Subtiligase Based Positive Selection		Wells	apopotic_Jurkat_FasL	23264352
Q13445-24-	AGPPPI...	24		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q13445-24-	AGPPPI...	24		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q13445-24-	AGPPPI...	24		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
Q13445-24-	AGPPPI...	24		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
Q13445-24-	AGPPPI...	24		N-TAILS		Overall Laboratory	Lange_Huesgen_et_al-RBC
Q13445-24-unknown	AGPPPI...	24	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q13445-146-unknown	MLDVKM...	146	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000464824

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...LLVAVL	209	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000467690
	...RPVPT	227	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)