Q15843: NEDD8
Protein names | - NEDD8 - Neddylin - Neural precursor cell expressed developmentally down-regulated protein 8 - NEDD-8 - Ubiquitin-like protein Nedd8 |
---|---|
Gene names | NEDD8 |
Organism | Homo sapiens |
Protease Family | |
Protease ID | |
Chromosome location | |
UniProt ID | Q15843 |
5
N-termini
3
C-termini
2
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MLIKVKTLTG KEIEIDIEPT DKVERIKERV EEKEGIPPQQ QRLIYSGKQM NDEKTAADYK
70 80
ILGGSVLHLV LALRGGGGLR Q
Isoforms
Sequence View
Protein Neighborhood
Domains & Features
5 N-termini - 3 C-termini - 2 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
Q15843-1-unknown | MLIKVK... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
Q15843-17-unknown | IEPTDK... | 17 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC19589 | |||
Q15843-34- | EGIPPQ... | 34 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
Q15843-43-unknown | LIYSGK... | 43 | unknown | Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage... | 18722006 | ||||
Q15843-43- | LIYSGK... | 43 | Subtiligase Based Positive Selection | Wells | DB_Untreated | 23264352 | |||
Q15843-43- | LIYSGK... | 43 | Subtiligase Based Positive Selection | Wells | apoptotic_DB_Doxo | 23264352 | |||
Q15843-43- | LIYSGK... | 43 | Subtiligase Based Positive Selection | Wells | apoptotic_RPMI_Dox | 23264352 |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...EIEIDI | 16 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC19589 | |||
...SGKQMN | 50 | inferred from electronic annotation | unknown | Ensembl | inferred from ensembl protein ENSP00000448192 | |||
...ALRGGG | 76 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
...ALRGGG | 76 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC31592 |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
MEP1B_HUMAN | 16 | EIDI.|.IEPT | inferred from experiment | unknown | MEROPS | Overall CM | Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002) | 21693781, |
SENP8_HUMAN | 76 | RGGG.|.GGLR | inferred from experiment | unknown | MEROPS | Hay RT | Mendoza HM et al.:NEDP1, a highly conserved cyste... (C48.011) | 12730221, |
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
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