Q60864: Stress-induced-phosphoprotein 1

General Information

Protein names	- Stress-induced-phosphoprotein 1 - STI1 - mSTI1 - Hsc70/Hsp90-organizing protein - Hop
Gene names	Stip1
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q60864

13 N-termini

8 C-termini

8 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MEQVNELKEK GNKALSAGNI DDALQCYSEA IKLDPQNHVL YSNRSAAYAK KGDYQKAYED
        70         80         90        100        110        120
GCKTVDLKPD WGKGYSRKAA ALEFLNRFEE AKRTYEEGLK HEANNLQLKE GLQNMEARLA
       130        140        150        160        170        180
ERKFMNPFNL PNLYQKLEND PRTRSLLSDP TYRELIEQLQ NKPSDLGTKL QDPRVMTTLS
       190        200        210        220        230        240
VLLGVDLGSM DEEEEAATPP PPPPPKKEPK PEPMEEDLPE NKKQALKEKE LGNDAYKKKD
       250        260        270        280        290        300
FDKALKHYDR AKELDPTNMT YITNQAAVHF EKGDYNKCRE LCEKAIEVGR ENREDYRQIA
       310        320        330        340        350        360
KAYARIGNSY FKEEKYKDAI HFYNKSLAEH RTPDVLKKCQ QAEKILKEQE RLAYINPDLA
       370        380        390        400        410        420
LEEKNKGNEC FQKGDYPQAM KHYTEAIKRN PRDAKLYSNR AACYTKLLEF QLALKDCEEC
       430        440        450        460        470        480
IQLEPTFIKG YTRKAAALEA MKDYTKAMDV YQKALDLDSS CKEAADGYQR CMMAQYNRHD
       490        500        510        520        530        540
SPEDVKRRAM ADPEVQQIMS DPAMRLILEQ MQKDPQALSE HLKNPVIAQK IQKLMDVGLI

AIR

Isoforms

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

13 N-termini - 8 C-termini - 8 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q60864-1-Acetylation	MEQVNE...	1	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q60864-14-unmodified	ALSAGN...	14			N-TAILS		Overall CM.	Prudova A.: Multiplex N-terminome analysis of MMP-2 and MMP-9...	20305284
Q60864-27-unknown	YSEAIK...	27		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC30475
Q60864-35-unknown	PQNHVL...	35		inferred from electronic annotation	unknown	TISdb		inferred from TISdb
Q60864-107-unknown	QLKEGL...	107		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC30476
Q60864-126-unknown	NPFNLP...	126		inferred from electronic annotation	unknown	TISdb		inferred from TISdb
Q60864-134-unknown	YQKLEN...	134		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29141
Q60864-265-unknown	QAAVHF...	265		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33923
Q60864-380-unknown	MKHYTE...	380		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33924
Q60864-421-unknown	IQLEPT...	421		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC30477
Q60864-421-unknown	IQLEPT...	421		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29142
Q60864-454-unknown	ALDLDS...	454			N-TAILS		Overall CM.	auf dem Keller U.: A statistics-based platform for quantitative N-terminome...	20305283
Q60864-454-unmodified	ALDLDS...	454			N-TAILS		Overall CM.	Prudova A.: Multiplex N-terminome analysis of MMP-2 and MMP-9...	20305284
Q60864-458-unknown	DSSCKE...	458		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC30478

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...DALQCY	26	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30475
...EANNLQ	106	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30476
...NLPNLY	133	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29141
...TYITNQ	264	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33923
...DYPQAM	379	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33924
...DCEECI	420	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30477
...DCEECI	420	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29142
...KALDLD	457	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30478
...LIAIR	543	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATE_MOUSE	26	LQCY.\|.YSEA	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> STIP1_MOUSE @26
CATE_MOUSE	106	NNLQ.\|.QLKE	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> STIP1_MOUSE @106
CATD_MOUSE	133	PNLY.\|.YQKL	inferred from experiment	unknown	MEROPS		Merops CATD_MOUSE -> STIP1_MOUSE @133
MMP2_MOUSE	264	ITNQ.\|.QAAV	inferred from experiment	unknown	MEROPS		Merops MMP2_MOUSE -> STIP1_MOUSE @264
MMP2_MOUSE	379	PQAM.\|.MKHY	inferred from experiment	unknown	MEROPS	Overall CM	Prudova A et al.:Multiplex N-terminome analysis ... (M10.004)	20305284,
CATE_MOUSE	420	EECI.\|.IQLE	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> STIP1_MOUSE @420
CATD_MOUSE	420	EECI.\|.IQLE	inferred from experiment	unknown	MEROPS		Merops CATD_MOUSE -> STIP1_MOUSE @420
CATE_MOUSE	457	LDLD.\|.DSSC	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> STIP1_MOUSE @457

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)