Q61207: Prosaposin

General Information

Protein names	- Prosaposin - Sulfated glycoprotein 1 - SGP-1 - Saposin-A - Saposin-B-Val - Saposin-B - Saposin-C - Saposin-D
Gene names	Psap
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q61207

8 N-termini

4 C-termini

3 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MYALALFASL LATALTSPVQ DPKTCSGGSA VLCRDVKTAV DCGAVKHCQQ MVWSKPTAKS
        70         80         90        100        110        120
LPCDICKTVV TEAGNLLKDN ATQEEILHYL EKTCEWIHDS SLSASCKEVV DSYLPVILDM
       130        140        150        160        170        180
IKGEMSNPGE VCSALNLCQS LQEYLAEQNQ KQLESNKIPE VDMARVVAPF MSNIPLLLYP
       190        200        210        220        230        240
QDHPRSQPQP KANEDVCQDC MKLVSDVQTA VKTNSSFIQG FVDHVKEDCD RLGPGVSDIC
       250        260        270        280        290        300
KNYVDQYSEV CVQMLMHMQD QQPKEICVLA GFCNEVKRVP MKTLVPATET IKNILPALEM
       310        320        330        340        350        360
MDPYEQNLVQ AHNVILCQTC QFVMNKFSEL IVNNATEELL VKGLSNACAL LPDPARTKCQ
       370        380        390        400        410        420
EVVGTFGPSL LDIFIHEVNP SSLCGVIGLC AARPELVEAL EQPAPAIVSA LLKEPTPPKQ
       430        440        450        460        470        480
PAQPKQSALP AHVPPQKNGG FCEVCKKLVL YLEHNLEKNS TKEEILAALE KGCSFLPDPY
       490        500        510        520        530        540
QKQCDDFVAE YEPLLLEILV EVMDPGFVCS KIGVCPSAYK LLLGTEKCVW GPSYWCQNME
       550
TAARCNAVDH CKRHVWN

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

8 N-termini - 4 C-termini - 3 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q61207-17-unknown	SPVQDP...	17	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q61207-17-unknown	SPVQDP...	17	inferred from similarity	unknown	UniProtKB		inferred from uniprot (by similarity)
Q61207-17-unknown	SPVQDP...	17		N-TAILS		Overall CM.	auf dem Keller U.: A statistics-based platform for quantitative N-terminome...	20305283
Q61207-17-unmodified	SPVQDP...	17		N-TAILS		Overall CM.	Kleifeldt O. et al.: Isotopic labeling of terminal amines in complex samples identifies...	20208520
Q61207-17-unmodified	SPVQDP...	17		unknown			Kleifeldt O. et al.: N-terminome analysis of bronchoalveolar lavage fluids collected from...	20208520
Q61207-17-unmodified	SPVQDP...	17		N-TAILS		Overall CM.	Prudova A.: Multiplex N-terminome analysis of MMP-2 and MMP-9...	20305284
Q61207-27-unknown	GGSAVL...	27	inferred from electronic annotation	unknown	TISdb		inferred from TISdb
Q61207-129-unknown	GEVCSA...	129	inferred from electronic annotation	unknown	TISdb		inferred from TISdb
Q61207-148-unknown	QNQKQL...	148	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33946
Q61207-170-unknown	FMSNIP...	170	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33947
Q61207-175-unknown	PLLLYP...	175	inferred from electronic annotation	unknown	TISdb		inferred from TISdb
Q61207-521-unknown	LLLGTE...	521	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33948

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...EYLAEQ	147	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33946
...RVVAPF	169	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33947
...PSAYKL	520	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33948
...RHVWN	557	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MMP2_MOUSE	147	LAEQ.\|.QNQK	inferred from experiment	unknown	MEROPS		Merops MMP2_MOUSE -> SAP_MOUSE @147
MMP2_MOUSE	169	VAPF.\|.FMSN	inferred from experiment	unknown	MEROPS	Overall CM	Prudova A et al.:Multiplex N-terminome analysis ... (M10.004)	20305284,
MMP2_MOUSE	520	AYKL.\|.LLLG	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)