Q62422: Osteoclast-stimulating factor 1

General Information

Protein names	- Osteoclast-stimulating factor 1 - SH3 domain protein 3
Gene names	Ostf1
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q62422

9 N-termini

7 C-termini

6 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MSKPPPKPVK PGQVKVFRAL YTFEPRTPDE LYFEEGDIIY ITDMSDTSWW KGTCKGRTGL
        70         80         90        100        110        120
IPSNYVAEQA ESIDNPLHEA AKRGNLSWLR ECLDNRVGVN GLDKAGSTAL YWACHGGHKD
       130        140        150        160        170        180
IVEVLFTQPN VELNQQNKLG DTALHAAAWK GYADIVQLLL AKGARTDLRN NEKKLALDMA
       190        200        210
TNAACASLLK KKQQGTDGAR TLSNAEDYLD DEDSD

Isoforms

Sequence View

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Protease Assignment Confidence:

Evidence Names:

Database:

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Protein Neighborhood

Domains & Features

9 N-termini - 7 C-termini - 6 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q62422-2-unknown	MSKPPP...	1		inferred from similarity	unknown	UniProtKB		inferred from uniprot (by similarity)
Q62422-2-unknown	MSKPPP...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q62422-2-Acetylation	SKPPPK...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q62422-2-Acetylation	SKPPPK...	2	acetylation-	inferred from similarity	unknown	UniProtKB		inferred from uniprot (by similarity)
Q62422-19-unknown	ALYTFE...	19			N-TAILS		Overall CM.	auf dem Keller U.: A statistics-based platform for quantitative N-terminome...	20305283
Q62422-65-unknown	YVAEQA...	65		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33996
Q62422-66-unknown	VAEQAE...	66		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29173
Q62422-159-unknown	LLAKGA...	159		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29174
Q62422-176-unknown	ALDMAT...	176		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC30549
Q62422-180-unknown	ATNAAC...	180		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC30550
Q62422-182-unknown	NAACAS...	182		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC30551

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...LIPSNY	64	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33996
...IPSNYV	65	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29173
...DIVQLL	158	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29174
...NEKKLA	175	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30549
...LALDMA	179	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30550
...LDMATN	181	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30551
...DEDSD	215	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MMP2_MOUSE	64	PSNY.\|.YVAE	inferred from experiment	unknown	MEROPS	Overall CM	Prudova A et al.:Multiplex N-terminome analysis ... (M10.004)	20305284,
CATD_MOUSE	65	SNYV.\|.VAEQ	inferred from experiment	unknown	MEROPS		Merops CATD_MOUSE -> OSTF1_MOUSE @65
CATD_MOUSE	158	VQLL.\|.LLAK	inferred from experiment	unknown	MEROPS		Merops CATD_MOUSE -> OSTF1_MOUSE @158
CATE_MOUSE	175	KKLA.\|.ALDM	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> OSTF1_MOUSE @175
CATE_MOUSE	179	LDMA.\|.ATNA	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> OSTF1_MOUSE @179
CATE_MOUSE	181	MATN.\|.NAAC	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> OSTF1_MOUSE @181

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)