TopFIND 4.0

Q92667: A-kinase anchor protein 1, mitochondrial

General Information

Protein names
- A-kinase anchor protein 1, mitochondrial
- A-kinase anchor protein 149 kDa
- AKAP 149 {ECO:0000303|PubMed:8769136}
- Dual specificity A-kinase-anchoring protein 1
- D-AKAP-1
- Protein kinase A-anchoring protein 1
- PRKA1
- Spermatid A-kinase anchor protein 84
- S-AKAP84 {ECO:0000303|PubMed:7499250}
Gene names AKAP1
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q92667

5

N-termini

2

C-termini

4

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MAIQFRSLFP LALPGMLALL GWWWFFSRKK GHVSSHDEQQ VEAGAVQLRA DPAIKEPLPV 
        70         80         90        100        110        120 
EDVCPKVVST PPSVTEPPEK ELSTVSKLPA EPPALLQTHP PCRRSESSGI LPNTTDMRLR 
       130        140        150        160        170        180 
PGTRRDDSTK LELALTGGEA KSIPLECPLS SPKGVLFSSK SAEVCKQDSP FSRVPRKVQP 
       190        200        210        220        230        240 
GYPVVPAEKR SSGERARETG GAEGTGDAVL GEKVLEEALL SREHVLELEN SKGPSLASLE 
       250        260        270        280        290        300 
GEEDKGKSSS SQVVGPVQEE EYVAEKLPSR FIESAHTELA KDDAAPAPPV ADAKAQDRGV 
       310        320        330        340        350        360 
EGELGNEESL DRNEEGLDRN EEGLDRNEES LDRNEEGLDR NEEIKRAAFQ IISQVISEAT 
       370        380        390        400        410        420 
EQVLATTVGK VAGRVCQASQ LQGQKEESCV PVHQKTVLGP DTAEPATAEA AVAPPDAGLP 
       430        440        450        460        470        480 
LPGLPAEGSP PPKTYVSCLK SLLSSPTKDS KPNISAHHIS LASCLALTTP SEELPDRAGI 
       490        500        510        520        530        540 
LVEDATCVTC MSDSSQSVPL VASPGHCSDS FSTSGLEDSC TETSSSPRDK AITPPLPEST 
       550        560        570        580        590        600 
VPFSNGVLKG ELSDLGAEDG WTMDAEADHS GGSDRNSMDS VDSCCSLKKT ESFQNAQAGS 
       610        620        630        640        650        660 
NPKKVDLIIW EIEVPKHLVG RLIGKQGRYV SFLKQTSGAK IYISTLPYTQ SVQICHIEGS 
       670        680        690        700        710        720 
QHHVDKALNL IGKKFKELNL TNIYAPPLPS LALPSLPMTS WLMLPDGITV EVIVVNQVNA 
       730        740        750        760        770        780 
GHLFVQQHTH PTFHALRSLD QQMYLCYSQP GIPTLPTPVE ITVICAAPGA DGAWWRAQVV 
       790        800        810        820        830        840 
ASYEETNEVE IRYVDYGGYK RVKVDVLRQI RSDFVTLPFQ GAEVLLDSVM PLSDDDQFSP 
       850        860        870        880        890        900 
EADAAMSEMT GNTALLAQVT SYSPTGLPLI QLWSVVGDEV VLINRSLVER GLAQWVDSYY 
   
TSL

Isoforms

- Isoform 2 of A-kinase anchor protein 1, mitochondrial

Sequence View

        10         20         30         40         50         60 
MAIQFRSLFP LALPGMLALL GWWWFFSRKK GHVSSHDEQQ VEAGAVQLRA DPAIKEPLPV 
        70         80         90        100        110        120 
EDVCPKVVST PPSVTEPPEK ELSTVSKLPA EPPALLQTHP PCRRSESSGI LPNTTDMRLR 
       130        140        150        160        170        180 
PGTRRDDSTK LELALTGGEA KSIPLECPLS SPKGVLFSSK SAEVCKQDSP FSRVPRKVQP 
       190        200        210        220        230        240 
GYPVVPAEKR SSGERARETG GAEGTGDAVL GEKVLEEALL SREHVLELEN SKGPSLASLE 
       250        260        270        280        290        300 
GEEDKGKSSS SQVVGPVQEE EYVAEKLPSR FIESAHTELA KDDAAPAPPV ADAKAQDRGV 
       310        320        330        340        350        360 
EGELGNEESL DRNEEGLDRN EEGLDRNEES LDRNEEGLDR NEEIKRAAFQ IISQVISEAT 
       370        380        390        400        410        420 
EQVLATTVGK VAGRVCQASQ LQGQKEESCV PVHQKTVLGP DTAEPATAEA AVAPPDAGLP 
       430        440        450        460        470        480 
LPGLPAEGSP PPKTYVSCLK SLLSSPTKDS KPNISAHHIS LASCLALTTP SEELPDRAGI 
       490        500        510        520        530        540 
LVEDATCVTC MSDSSQSVPL VASPGHCSDS FSTSGLEDSC TETSSSPRDK AITPPLPEST 
       550        560        570        580        590        600 
VPFSNGVLKG ELSDLGAEDG WTMDAEADHS GGSDRNSMDS VDSCCSLKKT ESFQNAQAGS 
       610        620        630        640        650        660 
NPKKVDLIIW EIEVPKHLVG RLIGKQGRYV SFLKQTSGAK IYISTLPYTQ SVQICHIEGS 
       670        680        690        700        710        720 
QHHVDKALNL IGKKFKELNL TNIYAPPLPS LALPSLPMTS WLMLPDGITV EVIVVNQVNA 
       730        740        750        760        770        780 
GHLFVQQHTH PTFHALRSLD QQMYLCYSQP GIPTLPTPVE ITVICAAPGA DGAWWRAQVV 
       790        800        810        820        830        840 
ASYEETNEVE IRYVDYGGYK RVKVDVLRQI RSDFVTLPFQ GAEVLLDSVM PLSDDDQFSP 
       850        860        870        880        890        900 
EADAAMSEMT GNTALLAQVT SYSPTGLPLI QLWSVVGDEV VLINRSLVER GLAQWVDSYY 
   
TSL



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Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


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Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

5 N-termini - 2 C-termini - 4 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)