Q99757: Thioredoxin, mitochondrial
Protein names | - Thioredoxin, mitochondrial - MTRX - Mt-Trx - Thioredoxin-2 |
---|---|
Gene names | TXN2 |
Organism | Homo sapiens |
Protease Family | |
Protease ID | |
Chromosome location | |
UniProt ID | Q99757 |
6
N-termini
2
C-termini
1
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MAQRLLLRRF LASVISRKPS QGQWPPLTSR ALQTPQCSPG GLTVTPNPAR TIYTTRISLT
70 80 90 100 110 120
TFNIQDGPDF QDRVVNSETP VVVDFHAQWC GPCKILGPRL EKMVAKQHGK VVMAKVDIDD
130 140 150 160
HTDLAIEYEV SAVPTVLAMK NGDVVDKFVG IKDEDQLEAF LKKLIG
Isoforms
Sequence View
Protein Neighborhood
Domains & Features
6 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
Q99757-60- | TTFNIQ... | 60 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_bortezomib | 23264352 | |||
Q99757-60- | TTFNIQ... | 60 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
Q99757-60- | TTFNIQ... | 60 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1s_bort | 23264352 | |||
Q99757-60- | TTFNIQ... | 60 | Subtiligase Based Positive Selection | Wells | MM1SDBJurkat_Untreated | 23264352 | |||
Q99757-60- | TTFNIQ... | 60 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1SDBJurkat_Mix | 23264352 | |||
Q99757-60- | TTFNIQ... | 60 | Subtiligase Based Positive Selection | Wells | apoptosis_U266_bortezomib_induced | 23264352 | |||
Q99757-60-unknown | TTFNIQ... | 60 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
Q99757-62- | FNIQDG... | 62 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
Q99757-63- | NIQDGP... | 63 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
Q99757-103-unknown | MVAKQH... | 103 | inferred from electronic annotation | unknown | Ensembl | inferred from ensembl protein ENSP00000469160 | |||
Q99757-143-unknown | DVVDKF... | 143 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC19753 |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...AMKNGD | 142 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC19753 | |||
...KKLIG | 166 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
MEP1B_HUMAN | 142 | KNGD.|.DVVD | inferred from experiment | unknown | MEROPS | Overall CM | Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002) | 21693781, |
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|