Q99KJ8: Dynactin subunit 2

General Information

Protein names	- Dynactin subunit 2 - 50 kDa dynein-associated polypeptide - Dynactin complex 50 kDa subunit - DCTN-50 - Growth cone membrane protein 23-48K - GMP23-48K - p50 dynamitin
Gene names	Dctn2
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q99KJ8

9 N-termini

6 C-termini

7 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MADPKYADLP GIARNEPDVY ETSDLPEDDQ AEFDAEELSS TSVEHIIVNP NAAYDKFKDK
        70         80         90        100        110        120
RVGTKGLDFS DRIGKTKRTG YESGDYEMLG EGLGVKETPQ QKYQRLLHEV QELTTEVEKI
       130        140        150        160        170        180
KTTVKESATE EKLTPVVLAK QLAALKQQLV ASHLEKLLGP DAAINLADPD GALAKRLLLQ
       190        200        210        220        230        240
LEATKSSKGS SGGKATAGAP PDSSLVTYEL HSRPEQDKFS QAAKVAELEK RLTELEATVR
       250        260        270        280        290        300
CDQDAQNPLS AGLQGACLME TVELLQAKVS ALDLAVLDQV EARLQSVLGK VNEIAKHKAS
       310        320        330        340        350        360
VEDADTQNKV HQLYETIQRW SPVASTLPEL VQRLVTIKQL HEQAMQFGQL LTHLDTTQQM
       370        380        390        400
MASSLKDNTA LLTQVQTTMR ENLATVEGNF ASIDARMKRL GK

Isoforms

Sequence View

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Evidence Names:

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Protein Neighborhood

Domains & Features

9 N-termini - 6 C-termini - 7 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q99KJ8-2-unknown	MADPKY...	1		inferred from similarity	unknown	UniProtKB		inferred from uniprot (by similarity)
Q99KJ8-2-unknown	MADPKY...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q99KJ8-2-Acetylation	ADPKYA...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q99KJ8-2-Acetylation	ADPKYA...	2	acetylation-		N-TAILS		Overall CM.	auf dem Keller U.: A statistics-based platform for quantitative N-terminome...	20305283
Q99KJ8-2-Acetylation	ADPKYA...	2	acetylation-		N-TAILS		Overall CM.	Prudova A.: Multiplex N-terminome analysis of MMP-2 and MMP-9...	20305284
Q99KJ8-2-Acetylation	ADPKYA...	2	acetylation-	inferred from similarity	unknown	UniProtKB		inferred from uniprot (by similarity)
Q99KJ8-39-unknown	SSTSVE...	39		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29307
Q99KJ8-89-unknown	LGEGLG...	89		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC30966
Q99KJ8-90-unknown	GEGLGV...	90		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29308
Q99KJ8-90-unknown	GEGLGV...	90		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC30967
Q99KJ8-125-unknown	KESATE...	125		inferred from electronic annotation	unknown	TISdb		inferred from TISdb
Q99KJ8-157-unknown	LLGPDA...	157		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC34168
Q99KJ8-299-unmodified	ASVEDA...	299			N-TAILS		Overall CM.	Prudova A.: Multiplex N-terminome analysis of MMP-2 and MMP-9...	20305284
Q99KJ8-372-unknown	LTQVQT...	372		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29309
Q99KJ8-372-unknown	LTQVQT...	372		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC30968

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...DAEELS	38	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29307
...GDYEML	88	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30966
...DYEMLG	89	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29308
...DYEMLG	89	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30967
...SHLEKL	156	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34168
...DNTALL	371	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29309
...DNTALL	371	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30968
...KRLGK	402	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Evidence name
CATD_MOUSE	38	EELS.\|.SSTS	inferred from experiment	unknown	MEROPS	Merops CATD_MOUSE -> DCTN2_MOUSE @38
CATE_MOUSE	88	YEML.\|.LGEG	inferred from experiment	unknown	MEROPS	Merops CATE_MOUSE -> DCTN2_MOUSE @88
CATD_MOUSE	89	EMLG.\|.GEGL	inferred from experiment	unknown	MEROPS	Merops CATD_MOUSE -> DCTN2_MOUSE @89
CATE_MOUSE	89	EMLG.\|.GEGL	inferred from experiment	unknown	MEROPS	Merops CATE_MOUSE -> DCTN2_MOUSE @89
MMP2_MOUSE	156	LEKL.\|.LLGP	inferred from experiment	unknown	MEROPS	Merops MMP2_MOUSE -> DCTN2_MOUSE @156
CATD_MOUSE	371	TALL.\|.LTQV	inferred from experiment	unknown	MEROPS	Merops CATD_MOUSE -> DCTN2_MOUSE @371
CATE_MOUSE	371	TALL.\|.LTQV	inferred from experiment	unknown	MEROPS	Merops CATE_MOUSE -> DCTN2_MOUSE @371

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)