Q9BQT9: Calsyntenin-3

General Information

Protein names	- Calsyntenin-3 - Alcadein-beta - Alc-beta
Gene names	CLSTN3
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9BQT9

4 N-termini

4 C-termini

6 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MTLLLLPLLL ASLLASCSCN KANKHKPWIE AEYQGIVMEN DNTVLLNPPL FALDKDAPLR
        70         80         90        100        110        120
YAGEICGFRL HGSGVPFEAV ILDKATGEGL IRAKEPVDCE AQKEHTFTIQ AYDCGEGPDG
       130        140        150        160        170        180
ANTKKSHKAT VHVRVNDVNE FAPVFVERLY RAAVTEGKLY DRILRVEAID GDCSPQYSQI
       190        200        210        220        230        240
CYYEILTPNT PFLIDNDGNI ENTEKLQYSG ERLYKFTVTA YDCGKKRAAD DAEVEIQVKP
       250        260        270        280        290        300
TCKPSWQGWN KRIEYAPGAG SLALFPGIRL ETCDEPLWNI QATIELQTSH VAKGCDRDNY
       310        320        330        340        350        360
SERALRKLCG AATGEVDLLP MPGPNANWTA GLSVHYSQDS SLIYWFNGTQ AVQVPLGGPS
       370        380        390        400        410        420
GLGSGPQDSL SDHFTLSFWM KHGVTPNKGK KEEETIVCNT VQNEDGFSHY SLTVHGCRIA
       430        440        450        460        470        480
FLYWPLLESA RPVKFLWKLE QVCDDEWHHY ALNLEFPTVT LYTDGISFDP ALIHDNGLIH
       490        500        510        520        530        540
PPRREPALMI GACWTEEKNK EKEKGDNSTD TTQGDPLSIH HYFHGYLAGF SVRSGRLESR
       550        560        570        580        590        600
EVIECLYACR EGLDYRDFES LGKGMKVHVN PSQSLLTLEG DDVETFNHAL QHVAYMNTLR
       610        620        630        640        650        660
FATPGVRPLR LTTAVKCFSE ESCVSIPEVE GYVVVLQPDA PQILLSGTAH FARPAVDFEG
       670        680        690        700        710        720
TNGVPLFPDL QITCSISHQV EAKKDESWQG TVTDTRMSDE IVHNLDGCEI SLVGDDLDPE
       730        740        750        760        770        780
RESLLLDTTS LQQRGLELTN TSAYLTIAGV ESITVYEEIL RQARYRLRHG AALYTRKFRL
       790        800        810        820        830        840
SCSEMNGRYS SNEFIVEVNV LHSMNRVAHP SHVLSSQQFL HRGHQPPPEM AGHSLASSHR
       850        860        870        880        890        900
NSMIPSAATL IIVVCVGFLV LMVVLGLVRI HSLHRRVSGA GGPPGASSDP KDPDLFWDDS
       910        920        930        940        950
ALTIIVNPME SYQNRQSCVT GAVGGQQEDE DSSDSEVADS PSSDERRIIE TPPHRY

Isoforms

- Isoform 2 of Calsyntenin-3

Sequence View

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Protein Neighborhood

Domains & Features

4 N-termini - 4 C-termini - 6 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q9BQT9-20-unknown	NKANKH...	20	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q9BQT9-813-unknown	VLSSQQ...	813	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC99
Q9BQT9-813-unknown	VLSSQQ...	813	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC147
Q9BQT9-813-unknown	VLSSQQ...	813	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt156582
Q9BQT9-850-unknown	LIIVVC...	850	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC101
Q9BQT9-850-unknown	LIIVVC...	850	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC149
Q9BQT9-850-unknown	LIIVVC...	850	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt156718
Q9BQT9-853-unknown	VVCVGF...	853	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC103
Q9BQT9-853-unknown	VVCVGF...	853	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC151
Q9BQT9-853-unknown	VVCVGF...	853	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt156727

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...AHPSHV	812	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC99
...AHPSHV	812	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC147
...AHPSHV	812	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt140067
...PSAATL	849	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC101
...PSAATL	849	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC149
...PSAATL	849	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt140206
...ATLIIV	852	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC103
...ATLIIV	852	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC151
...ATLIIV	852	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt140215
...PPHRY	956	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...PPHRY	956	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt67568

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
ADA10_HUMAN	812	PSHV.\|.VLSS	inferred from experiment	unknown	MEROPS	Suzuki T	Hata S et al.:Alcadein cleavages by amyloid b... (M12.210)	19864413,
ADA17_HUMAN	812	PSHV.\|.VLSS	inferred from experiment	unknown	MEROPS	Suzuki T	Hata S et al.:Alcadein cleavages by amyloid b... (M12.210)	19864413,
ADA10_HUMAN	849	AATL.\|.LIIV	inferred from experiment	unknown	MEROPS	Suzuki T	Hata S et al.:Alcadein cleavages by amyloid b... (M12.210)	19864413,
ADA17_HUMAN	849	AATL.\|.LIIV	inferred from experiment	unknown	MEROPS	Suzuki T	Hata S et al.:Alcadein cleavages by amyloid b... (M12.210)	19864413,
ADA10_HUMAN	852	LIIV.\|.VVCV	inferred from experiment	unknown	MEROPS	Suzuki T	Hata S et al.:Alcadein cleavages by amyloid b... (M12.210)	19864413,
ADA17_HUMAN	852	LIIV.\|.VVCV	inferred from experiment	unknown	MEROPS	Suzuki T	Hata S et al.:Alcadein cleavages by amyloid b... (M12.210)	19864413,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)