Q9H1E5: Thioredoxin-related transmembrane protein 4

General Information

Protein names	- Thioredoxin-related transmembrane protein 4 - Thioredoxin domain-containing protein 13
Gene names	TMX4
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9H1E5

2 N-termini

2 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAGGRCGPQL TALLAAWIAA VAATAGPEEA ALPPEQSRVQ PMTASNWTLV MEGEWMLKFY
        70         80         90        100        110        120
APWCPSCQQT DSEWEAFAKN GEILQISVGK VDVIQEPGLS GRFFVTTLPA FFHAKDGIFR
       130        140        150        160        170        180
RYRGPGIFED LQNYILEKKW QSVEPLTGWK SPASLTMSGM AGLFSISGKI WHLHNYFTVT
       190        200        210        220        230        240
LGIPAWCSYV FFVIATLVFG LFMGLVLVVI SECFYVPLPR HLSERSEQNR RSEEAHRAEQ
       250        260        270        280        290        300
LQDAEEEKDD SNEEENKDSL VDDEEEKEDL GDEDEAEEEE EEDNLAAGVD EERSEANDQG
       310        320        330        340
PPGEDGVTRE EVEPEEAEEG ISEQPCPADT EVVEDSLRQR KSQHADKGL

Isoforms

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

2 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q9H1E5-24-unknown	TAGPEE...	24	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9H1E5-24-unknown	TAGPEE...	24		unknown			Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
Q9H1E5-24-unknown	TAGPEE...	24		unknown			Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
Q9H1E5-24-	TAGPEE...	24		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_Etoposide	23264352
Q9H1E5-24-	TAGPEE...	24		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
Q9H1E5-24-	TAGPEE...	24		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q9H1E5-24-	TAGPEE...	24		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
Q9H1E5-24-	TAGPEE...	24		N-TAILS		Overall Laboratory	Lange_Huesgen_et_al-RBC

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...LSERSE	226	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000435735
	...ADKGL	349	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)