Q9H4D0: Calsyntenin-2

General Information

Protein names	- Calsyntenin-2 - Alcadein-gamma - Alc-gamma
Gene names	CLSTN2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9H4D0

4 N-termini

4 C-termini

6 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MLPGRLCWVP LLLALGVGSG SGGGGDSRQR RLLAAKVNKH KPWIETSYHG VITENNDTVI
        70         80         90        100        110        120
LDPPLVALDK DAPVPFAGEI CAFKIHGQEL PFEAVVLNKT SGEGRLRAKS PIDCELQKEY
       130        140        150        160        170        180
TFIIQAYDCG AGPHETAWKK SHKAVVHIQV KDVNEFAPTF KEPAYKAVVT EGKIYDSILQ
       190        200        210        220        230        240
VEAIDEDCSP QYSQICNYEI VTTDVPFAID RNGNIRNTEK LSYDKQHQYE ILVTAYDCGQ
       250        260        270        280        290        300
KPAAQDTLVQ VDVKPVCKPG WQDWTKRIEY QPGSGSMPLF PSIHLETCDG AVSSLQIVTE
       310        320        330        340        350        360
LQTNYIGKGC DRETYSEKSL QKLCGASSGI IDLLPSPSAA TNWTAGLLVD SSEMIFKFDG
       370        380        390        400        410        420
RQGAKVPDGI VPKNLTDQFT ITMWMKHGPS PGVRAEKETI LCNSDKTEMN RHHYALYVHN
       430        440        450        460        470        480
CRLVFLLRKD FDQADTFRPA EFHWKLDQIC DKEWHYYVIN VEFPVVTLYM DGATYEPYLV
       490        500        510        520        530        540
TNDWPIHPSH IAMQLTVGAC WQGGEVTKPQ FAQFFHGSLA SLTIRPGKME SQKVISCLQA
       550        560        570        580        590        600
CKEGLDINSL ESLGQGIKYH FNPSQSILVM EGDDIGNINR ALQKVSYINS RQFPTAGVRR
       610        620        630        640        650        660
LKVSSKVQCF GEDVCISIPE VDAYVMVLQA IEPRITLRGT DHFWRPAAQF ESARGVTLFP
       670        680        690        700        710        720
DIKIVSTFAK TEAPGDVKTT DPKSEVLEEM LHNLDFCDIL VIGGDLDPRQ ECLELNHSEL
       730        740        750        760        770        780
HQRHLDATNS TAGYSIYGVG SMSRYEQVLH HIRYRNWRPA SLEARRFRIK CSELNGRYTS
       790        800        810        820        830        840
NEFNLEVSIL HEDQVSDKEH VNHLIVQPPF LQSVHHPESR SSIQHSSVVP SIATVVIIIS
       850        860        870        880        890        900
VCMLVFVVAM GVYRVRIAHQ HFIQETEAAK ESEMDWDDSA LTITVNPMEK HEGPGHGEDE
       910        920        930        940        950
TEGEEEEEAE EEMSSSSGSD DSEEEEEEEG MGRGRHGQNG ARQAQLEWDD STLPY

Isoforms

Sequence View

Protein Neighborhood

Domains & Features

4 N-termini - 4 C-termini - 6 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q9H4D0-21-unknown	SGGGGD...	21	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q9H4D0-804-unknown	LIVQPP...	804	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC105
Q9H4D0-804-unknown	LIVQPP...	804	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC153
Q9H4D0-835-unknown	VVIIIS...	835	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC106
Q9H4D0-835-unknown	VVIIIS...	835	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC154
Q9H4D0-838-unknown	IISVCM...	838	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC107
Q9H4D0-838-unknown	IISVCM...	838	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC155

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...EHVNHL	803	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC105
...EHVNHL	803	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC153
...PSIATV	834	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC106
...PSIATV	834	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC154
...ATVVII	837	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC107
...ATVVII	837	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC155
...STLPY	955	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
ADA10_HUMAN	803	VNHL.\|.LIVQ	inferred from experiment	unknown	MEROPS	Suzuki T	Hata S et al.:Alcadein cleavages by amyloid b... (M12.210)	19864413,
ADA17_HUMAN	803	VNHL.\|.LIVQ	inferred from experiment	unknown	MEROPS	Suzuki T	Hata S et al.:Alcadein cleavages by amyloid b... (M12.210)	19864413,
ADA10_HUMAN	834	IATV.\|.VVII	inferred from experiment	unknown	MEROPS	Suzuki T	Hata S et al.:Alcadein cleavages by amyloid b... (M12.210)	19864413,
ADA17_HUMAN	834	IATV.\|.VVII	inferred from experiment	unknown	MEROPS	Suzuki T	Hata S et al.:Alcadein cleavages by amyloid b... (M12.210)	19864413,
ADA10_HUMAN	837	VVII.\|.IISV	inferred from experiment	unknown	MEROPS	Suzuki T	Hata S et al.:Alcadein cleavages by amyloid b... (M12.210)	19864413,
ADA17_HUMAN	837	VVII.\|.IISV	inferred from experiment	unknown	MEROPS	Suzuki T	Hata S et al.:Alcadein cleavages by amyloid b... (M12.210)	19864413,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

TopFIND

Q9H4D0: Calsyntenin-2

General Information

4

N-termini

4

C-termini

6

Cleavages

0

Substrates

Sequence

Isoforms

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Protein Neighborhood

Domains & Features

4 N-termini - 4 C-termini - 6 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates