Q9UHD1: Cysteine and histidine-rich domain-containing protein 1

General Information

Protein names	- Cysteine and histidine-rich domain-containing protein 1 - CHORD domain-containing protein 1 - CHORD-containing protein 1 - CHP-1 - Protein morgana
Gene names	CHORDC1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9UHD1

9 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MALLCYNRGC GQRFDPETNS DDACTYHPGV PVFHDALKGW SCCKRRTTDF SDFLSIVGCT
        70         80         90        100        110        120
KGRHNSEKPP EPVKPEVKTT EKKELCELKP KFQEHIIQAP KPVEAIKRPS PDEPMTNLEL
       130        140        150        160        170        180
KISASLKQAL DKLKLSSGNE ENKKEEDNDE IKIGTSCKNG GCSKTYQGLE SLEEVCVYHS
       190        200        210        220        230        240
GVPIFHEGMK YWSCCRRKTS DFNTFLAQEG CTKGKHMWTK KDAGKKVVPC RHDWHQTGGE
       250        260        270        280        290        300
VTISVYAKNS LPELSRVEAN STLLNVHIVF EGEKEFDQNV KLWGVIDVKR SYVTMTATKI
       310        320        330
EITMRKAEPM QWASLELPAA KKQEKQKDAT TD

Isoforms

- Isoform 2 of Cysteine and histidine-rich domain-containing protein 1

Sequence View

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Protein Neighborhood

Domains & Features

9 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q9UHD1-1-unknown	MALLCY...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt70595
Q9UHD1-2-unknown	MALLCY...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9UHD1-2-Acetylation	ALLCYN...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9UHD1-2-Acetylation	ALLCYN...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
Q9UHD1-2-Acetylation	ALLCYN...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
Q9UHD1-2-Acetylation	ALLCYN...	2	acetylation-		N-TAILS		Overall Laboratory	Lange_Huesgen_et_al-RBC
Q9UHD1-2-Acetylation	ALLCYN...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt110489
Q9UHD1-66-	SEKPPE...	66			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q9UHD1-66-unknown	SEKPPE...	66		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt172593
Q9UHD1-99-unknown	APKPVE...	99		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC6837
Q9UHD1-99-unknown	APKPVE...	99		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt141310
Q9UHD1-105-unknown	AIKRPS...	105		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt178312
Q9UHD1-105-	AIKRPS...	105			Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
Q9UHD1-198-unknown	KTSDFN...	198			unknown			Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
Q9UHD1-198-unknown	KTSDFN...	198		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt159511

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...EHIIQA	98	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC6837
...EHIIQA	98	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt124475
...DATTD	332	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...DATTD	332	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt66213

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATL1_HUMAN	98	IIQA.\|.APKP	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)