Q9UJU6: Drebrin-like protein

General Information

Protein names	- Drebrin-like protein - Cervical SH3P7 - Cervical mucin-associated protein - Drebrin-F - HPK1-interacting protein of 55 kDa - HIP-55 - SH3 domain-containing protein 7
Gene names	DBNL
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9UJU6

16 N-termini

3 C-termini

2 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Drebrin-like protein - Isoform 3 of Drebrin-like protein - Isoform 4 of Drebrin-like protein - Isoform 5 of Drebrin-like protein - Isoform 6 of Drebrin-like protein

Sequence View

        10         20         30         40         50         60
MAANLSRNGP ALQEAYVRVV TEKSPTDWAL FTYEGNSNDI RVAGTGEGGL EEMVEELNSG
        70         80         90        100        110        120
KVMYAFCRVK DPNSGLPKFV LINWTGEGVN DVRKGACASH VSTMASFLKG AHVTINARAE
       130        140        150        160        170        180
EDVEPECIME KVAKASGANY SFHKESGRFQ DVGPQAPVGS VYQKTNAVSE IKRVGKDSFW
       190        200        210        220        230        240
AKAEKEEENR RLEEKRRAEE AQRQLEQERR ERELREAARR EQRYQEQGGE ASPQRTWEQQ
       250        260        270        280        290        300
QEVVSRNRNE QESAVHPREI FKQKERAMST TSISSPQPGK LRSPFLQKQL TQPETHFGRE
       310        320        330        340        350        360
PAAAISRPRA DLPAEEPAPS TPPCLVQAEE EAVYEEPPEQ ETFYEQPPLV QQQGAGSEHI
       370        380        390        400        410        420
DHHIQGQGLS GQGLCARALY DYQAADDTEI SFDPENLITG IEVIDEGWWR GYGPDGHFGM
       430
FPANYVELIE         10         20         30         40         50         60
MAANLSRNGP ALQEAYVRVV TEKSPTDWAL FTYEGNSNDI RVAGTGEGGL EEMVEELNSG
        70         80         90        100        110        120
KVMYAFCRVK DPNSGLPKFV LINWTGEGVN DVRKGACASH VSTMASFLKG AHVTINARAE
       130        140        150        160        170        180
EDVEPECIME KVAKASGANY SFHKESGRFQ DVGPQAPVGS VYQKTNAVSE IKRVGKDSFW
       190        200        210        220        230        240
AKAEKEEENR RLEEKRRAEE AQRQLEQERR ERELREAARR EQRYQEQGGE ASPQRTWEQQ
       250        260        270        280        290        300
QEVVSRNRNE QESAVHPREI FKQKERAMST TSISSPQPGK LRSPFLQKQL TQPETHFGRE
       310        320        330        340        350        360
PAAAISRPRA DLPAEEPAPS TPPCLVQAEE EAVYEEPPEQ ETFYEQPPLV QQQGAGSEHI
       370        380        390        400        410        420
DHHIQGQGLS GQGLCARALY DYQAADDTEI SFDPENLITG IEVIDEGWWR GYGPDGHFGM
       430
FPANYVELIE         10         20         30         40         50         60
MAANLSRNGP ALQEAYVRVV TEKSPTDWAL FTYEGNSNDI RVAGTGEGGL EEMVEELNSG
        70         80         90        100        110        120
KVMYAFCRVK DPNSGLPKFV LINWTGEGVN DVRKGACASH VSTMASFLKG AHVTINARAE
       130        140        150        160        170        180
EDVEPECIME KVAKASGANY SFHKESGRFQ DVGPQAPVGS VYQKTNAVSE IKRVGKDSFW
       190        200        210        220        230        240
AKAEKEEENR RLEEKRRAEE AQRQLEQERR ERELREAARR EQRYQEQGGE ASPQRTWEQQ
       250        260        270        280        290        300
QEVVSRNRNE QESAVHPREI FKQKERAMST TSISSPQPGK LRSPFLQKQL TQPETHFGRE
       310        320        330        340        350        360
PAAAISRPRA DLPAEEPAPS TPPCLVQAEE EAVYEEPPEQ ETFYEQPPLV QQQGAGSEHI
       370        380        390        400        410        420
DHHIQGQGLS GQGLCARALY DYQAADDTEI SFDPENLITG IEVIDEGWWR GYGPDGHFGM
       430
FPANYVELIE         10         20         30         40         50         60
MAANLSRNGP ALQEAYVRVV TEKSPTDWAL FTYEGNSNDI RVAGTGEGGL EEMVEELNSG
        70         80         90        100        110        120
KVMYAFCRVK DPNSGLPKFV LINWTGEGVN DVRKGACASH VSTMASFLKG AHVTINARAE
       130        140        150        160        170        180
EDVEPECIME KVAKASGANY SFHKESGRFQ DVGPQAPVGS VYQKTNAVSE IKRVGKDSFW
       190        200        210        220        230        240
AKAEKEEENR RLEEKRRAEE AQRQLEQERR ERELREAARR EQRYQEQGGE ASPQRTWEQQ
       250        260        270        280        290        300
QEVVSRNRNE QESAVHPREI FKQKERAMST TSISSPQPGK LRSPFLQKQL TQPETHFGRE
       310        320        330        340        350        360
PAAAISRPRA DLPAEEPAPS TPPCLVQAEE EAVYEEPPEQ ETFYEQPPLV QQQGAGSEHI
       370        380        390        400        410        420
DHHIQGQGLS GQGLCARALY DYQAADDTEI SFDPENLITG IEVIDEGWWR GYGPDGHFGM
       430
FPANYVELIE         10         20         30         40         50         60
MAANLSRNGP ALQEAYVRVV TEKSPTDWAL FTYEGNSNDI RVAGTGEGGL EEMVEELNSG
        70         80         90        100        110        120
KVMYAFCRVK DPNSGLPKFV LINWTGEGVN DVRKGACASH VSTMASFLKG AHVTINARAE
       130        140        150        160        170        180
EDVEPECIME KVAKASGANY SFHKESGRFQ DVGPQAPVGS VYQKTNAVSE IKRVGKDSFW
       190        200        210        220        230        240
AKAEKEEENR RLEEKRRAEE AQRQLEQERR ERELREAARR EQRYQEQGGE ASPQRTWEQQ
       250        260        270        280        290        300
QEVVSRNRNE QESAVHPREI FKQKERAMST TSISSPQPGK LRSPFLQKQL TQPETHFGRE
       310        320        330        340        350        360
PAAAISRPRA DLPAEEPAPS TPPCLVQAEE EAVYEEPPEQ ETFYEQPPLV QQQGAGSEHI
       370        380        390        400        410        420
DHHIQGQGLS GQGLCARALY DYQAADDTEI SFDPENLITG IEVIDEGWWR GYGPDGHFGM
       430
FPANYVELIE

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

16 N-termini - 3 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q9UJU6-1-unknown	MAANLS...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9UJU6-1-unknown	MAANLS...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt72383
Q9UJU6-1-unknown	MAANLS...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt72384
Q9UJU6-19-unknown	VVTEKS...	19	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt164214
Q9UJU6-19-unknown	VVTEKS...	19	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt164215
Q9UJU6-19-	VVTEKS...	19		Subtiligase Based Positive Selection		Wells	DB_Untreated	23264352
Q9UJU6-104-unknown	MASFLK...	104	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt72386
Q9UJU6-104-unknown	MASFLK...	104	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000415173
Q9UJU6-104-unknown	MASFLK...	104	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt106729
Q9UJU6-104-unknown	MASFLK...	104	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt106730
Q9UJU6-123-unknown	VEPECI...	123	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC19852
Q9UJU6-123-unknown	VEPECI...	123	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt136865
Q9UJU6-123-unknown	VEPECI...	123	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt137414
Q9UJU6-123-unknown	VEPECI...	123	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt143616
Q9UJU6-123-unknown	VEPECI...	123	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt143614
Q9UJU6-135-	ASGANY...	135		Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
Q9UJU6-135-	ASGANY...	135		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_Etoposide	23264352
Q9UJU6-135-	ASGANY...	135		Subtiligase Based Positive Selection		Wells	apoptotic_RPMI_Dox	23264352
Q9UJU6-135-unknown	ASGANY...	135		unknown			Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
Q9UJU6-135-unknown	ASGANY...	135	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt161437
Q9UJU6-135-unknown	ASGANY...	135	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt161438
Q9UJU6-135-unknown	ASGANY...	135	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt161439
Q9UJU6-135-unknown	ASGANY...	135	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt161440
Q9UJU6-174-	VGKDSF...	174		Subtiligase Based Positive Selection		Wells	DB_Untreated	23264352
Q9UJU6-174-unknown	VGKDSF...	174	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt164222
Q9UJU6-174-unknown	VGKDSF...	174	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt164223
Q9UJU6-174-unknown	VGKDSF...	174	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt164224
Q9UJU6-174-unknown	VGKDSF...	174	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt164225
Q9UJU6-267-	AMSTTS...	267		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q9UJU6-267-unknown	AMSTTS...	267	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt172847
Q9UJU6-267-unknown	AMSTTS...	267	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt172848
Q9UJU6-267-unknown	AMSTTS...	267	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt172850
Q9UJU6-267-unknown	AMSTTS...	267	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt172849
Q9UJU6-272-unknown	SISSPQ...	272	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt168162
Q9UJU6-272-unknown	SISSPQ...	272	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt168163
Q9UJU6-272-unknown	SISSPQ...	272	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt168165
Q9UJU6-272-unknown	SISSPQ...	272	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt168164
Q9UJU6-272-	SISSPQ...	272		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
Q9UJU6-272-	SISSPQ...	272		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
Q9UJU6-272-	SISSPQ...	272		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q9UJU6-272-	SISSPQ...	272		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
Q9UJU6-283-unknown	SPFLQK...	283	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt164217
Q9UJU6-283-unknown	SPFLQK...	283	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt164218
Q9UJU6-283-unknown	SPFLQK...	283	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt164220
Q9UJU6-283-unknown	SPFLQK...	283	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt164219
Q9UJU6-283-	SPFLQK...	283		Subtiligase Based Positive Selection		Wells	DB_Untreated	23264352
Q9UJU6-283-	SPFLQK...	283		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
Q9UJU6-362-unknown	HHIQGQ...	362	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC2341
Q9UJU6-362-unknown	HHIQGQ...	362	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt148763
Q9UJU6-362-unknown	HHIQGQ...	362	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt149066
Q9UJU6-362-unknown	HHIQGQ...	362	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt151247
Q9UJU6-362-unknown	HHIQGQ...	362	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt151425

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...RAEEDV	122	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC19852
...RAEEDV	122	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt126856
...RAEEDV	122	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt126858
...SEHIDH	361	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC2341
...SEHIDH	361	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt132139
...SEHIDH	361	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt132450
...SEHIDH	361	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt134649
...SEHIDH	361	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt134828
...VELIE	430	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...VELIE	430	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt68004
...VELIE	430	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt68003
...VELIE	430	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt68001
...VELIE	430	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt68002

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MEP1B_HUMAN	122	EEDV.\|.VEPE	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
CASP3_HUMAN	361	HIDH.\|.HHIQ	inferred from experiment	unknown	MEROPS	Tan TH	Chen YR et al.:Caspase-mediated cleavage of ac... (C14.003)	11689006,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)