TopFIND 4.0

O54732: Matrix metalloproteinase-15

General Information

Protein names
- Matrix metalloproteinase-15
- MMP-15
- 3.4.24.-
- Membrane-type matrix metalloproteinase 2
- MT-MMP 2
- MTMMP2
- Membrane-type-2 matrix metalloproteinase
- MT2-MMP
- MT2MMP
Gene names Mmp15
Organism Mus musculus
Protease Family M10.015
Protease ID M10.015
Chromosome location
UniProt ID O54732

2

N-termini

2

C-termini

5

Cleavages

50

Substrates

Sequence

        10         20         30         40         50         60 
MGSDRSALGR PGCTGSCLSS RASLLPLLLV LLDCLGHGTA SKDAEVYAAE NWLRLYGYLP 
        70         80         90        100        110        120 
QPSRHMSTMR SAQILASALA EMQSFYGIPV TGVLDEETKT WMKRPRCGVP DQFGVHVKAN 
       130        140        150        160        170        180 
LRRRRKRYTL TGKAWNNYHL TFSIQNYTEK LGWYNSMEAV RRAFQVWEQV TPLVFQEVSY 
       190        200        210        220        230        240 
DDIRLRRRAE ADIMVLFASG FHGDSSPFDG VGGFLAHAYF PGPGLGGDTH FDADEPWTFS 
       250        260        270        280        290        300 
STDLHGISLF LVAVHELGHA LGLEHSSNPS AIMAPFYQWM DTDNFQLPED DLRGIQQLYG 
       310        320        330        340        350        360 
SPDGKPQPTR PLPTVRPRRP GRPDHQPPRP PQPPHPGGKP ERPPKPGPPP QPRATERPDQ 
       370        380        390        400        410        420 
YGPNICDGNF DTVAVLRGEM FVFKGRWFWR VRHNRVLDNY PMPIGHFWRG LPGNISAAYE 
       430        440        450        460        470        480 
RQDGHFVFFK GNRYWLFREA NLEPGYPQPL SSYGTDIPYD RIDTAIWWEP TGHTFFFQAD 
       490        500        510        520        530        540 
RYWRFNEETQ HGDPGYPKPI SVWQGIPTSP KGAFLSNDAA YTYFYKGTKY WKFNNERLRM 
       550        560        570        580        590        600 
EPGHPKSILR DFMGCQEHVE PRSRWPDVAR PPFNPNGGAE PEADGDSKEE NAGDKDEGSR 
       610        620        630        640        650    
VVVQMEEVVR TVNVVMVLVP LLLLLCILGL AFALVQMQRK GAPRMLLYCK RSLQEWV

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

2 N-termini - 2 C-termini - 5 Cleavages - 50 Substrates

N-termini

C-termini

Cleavages

Substrates