O88569: Heterogeneous nuclear ribonucleoproteins A2/B1

General Information

Protein names	- Heterogeneous nuclear ribonucleoproteins A2/B1 - hnRNP A2/B1
Gene names	Hnrnpa2b1
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	O88569

15 N-termini

12 C-termini

12 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Heterogeneous nuclear ribonucleoproteins A2/B1 - Isoform 3 of Heterogeneous nuclear ribonucleoproteins A2/B1

Sequence View

        10         20         30         40         50         60
MEKTLETVPL ERKKREKEQF RKLFIGGLSF ETTEESLRNY YEQWGKLTDC VVMRDPASKR
        70         80         90        100        110        120
SRGFGFVTFS SMAEVDAAMA ARPHSIDGRV VEPKRAVARE ESGKPGAHVT VKKLFVGGIK
       130        140        150        160        170        180
EDTEEHHLRD YFEEYGKIDT IEIITDRQSG KKRGFGFVTF DDHDPVDKIV LQKYHTINGH
       190        200        210        220        230        240
NAEVRKALSR QEMQEVQSSR SGRGGNFGFG DSRGGGGNFG PGPGSNFRGG SDGYGSGRGF
       250        260        270        280        290        300
GDGYNGYGGG PGGGNFGGSP GYGGGRGGYG GGGPGYGNQG GGYGGGYDNY GGGNYGSGSY
       310        320        330        340        350
NDFGNYNQQP SNYGPMKSGN FGGSRNMGGP YGGGNYGPGG SGGSGGYGGR SRY         10         20         30         40         50         60
MEKTLETVPL ERKKREKEQF RKLFIGGLSF ETTEESLRNY YEQWGKLTDC VVMRDPASKR
        70         80         90        100        110        120
SRGFGFVTFS SMAEVDAAMA ARPHSIDGRV VEPKRAVARE ESGKPGAHVT VKKLFVGGIK
       130        140        150        160        170        180
EDTEEHHLRD YFEEYGKIDT IEIITDRQSG KKRGFGFVTF DDHDPVDKIV LQKYHTINGH
       190        200        210        220        230        240
NAEVRKALSR QEMQEVQSSR SGRGGNFGFG DSRGGGGNFG PGPGSNFRGG SDGYGSGRGF
       250        260        270        280        290        300
GDGYNGYGGG PGGGNFGGSP GYGGGRGGYG GGGPGYGNQG GGYGGGYDNY GGGNYGSGSY
       310        320        330        340        350
NDFGNYNQQP SNYGPMKSGN FGGSRNMGGP YGGGNYGPGG SGGSGGYGGR SRY

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

15 N-termini - 12 C-termini - 12 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
O88569-1-Acetylation	MEKTLE...	1	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
O88569-1-Acetylation	MEKTLE...	1	acetylation-		N-TAILS		Overall CM.	auf dem Keller U.: A statistics-based platform for quantitative N-terminome...	20305283
O88569-1-Acetylation	MEKTLE...	1	acetylation-		N-TAILS		Overall CM.	Kleifeldt O. et al.: Isotopic labeling of terminal amines in complex samples identifies...	20208520
O88569-1-Acetylation	MEKTLE...	1	acetylation-		unknown			Kleifeldt O. et al.: N-terminome analysis of bronchoalveolar lavage fluids collected from...	20208520
O88569-1-Acetylation	MEKTLE...	1	acetylation-		N-TAILS		Overall CM.	Prudova A.: Multiplex N-terminome analysis of MMP-2 and MMP-9...	20305284
O88569-22-unknown	KLFIGG...	22			N-TAILS		Overall CM.	auf dem Keller U.: A statistics-based platform for quantitative N-terminome...	20305283
O88569-22-unknown	KLFIGG...	22		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt160467
O88569-22-unknown	KLFIGG...	22		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt160468
O88569-28-unknown	LSFETT...	28		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33170
O88569-28-unknown	LSFETT...	28		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt136594
O88569-28-unknown	LSFETT...	28		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt136595
O88569-29-unknown	SFETTE...	29		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33173
O88569-29-unknown	SFETTE...	29		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt136643
O88569-29-unknown	SFETTE...	29		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt136644
O88569-47-unknown	LTDCVV...	47		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33176
O88569-47-unknown	LTDCVV...	47		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt137981
O88569-47-unknown	LTDCVV...	47		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt137982
O88569-64-unknown	FGFVTF...	64		inferred from electronic annotation	unknown	TISdb		inferred from TISdb
O88569-64-unknown	FGFVTF...	64		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt196388
O88569-64-unknown	FGFVTF...	64		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt196389
O88569-67-unknown	VTFSSM...	67		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29582
O88569-67-unknown	VTFSSM...	67		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt139542
O88569-67-unknown	VTFSSM...	67		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt139543
O88569-70-unknown	SSMAEV...	70		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC28680
O88569-70-unknown	SSMAEV...	70		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt139713
O88569-70-unknown	SSMAEV...	70		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt139714
O88569-73-unknown	AEVDAA...	73		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC28683
O88569-73-unknown	AEVDAA...	73		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29585
O88569-73-unknown	AEVDAA...	73		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt139965
O88569-73-unknown	AEVDAA...	73		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt139966
O88569-116-unknown	VGGIKE...	116			N-TAILS		Overall CM.	auf dem Keller U.: A statistics-based platform for quantitative N-terminome...	20305283
O88569-116-unknown	VGGIKE...	116		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt160506
O88569-116-unknown	VGGIKE...	116		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt160507
O88569-118-unknown	GIKEDT...	118		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33179
O88569-118-unknown	GIKEDT...	118		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt142700
O88569-118-unknown	GIKEDT...	118		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt142701
O88569-119-unknown	IKEDTE...	119		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33182
O88569-119-unknown	IKEDTE...	119		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt142767
O88569-119-unknown	IKEDTE...	119		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt142768
O88569-131-unknown	YFEEYG...	131		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33185
O88569-131-unknown	YFEEYG...	131		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt143430
O88569-131-unknown	YFEEYG...	131		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt143431
O88569-204-unknown	GGNFGF...	204		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33188
O88569-204-unknown	GGNFGF...	204		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt146322
O88569-204-unknown	GGNFGF...	204		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt146323
O88569-204-unknown	GGNFGF...	204		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
O88569-204-unknown	GGNFGF...	204		inferred from similarity	unknown	UniProtKB		inferred from uniprot (by similarity)
O88569-318-unknown	SGNFGG...	318		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29588
O88569-318-unknown	SGNFGG...	318		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt149025
O88569-318-unknown	SGNFGG...	318		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt150034

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...LFIGGL	27	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33170
...FIGGLS	28	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33173
...EQWGKL	46	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33176
...EQWGKL	46	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt120990
...EQWGKL	46	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt120991
...RGFGFV	66	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29582
...RGFGFV	66	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt122632
...RGFGFV	66	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt122633
...GFVTFS	69	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28680
...GFVTFS	69	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt122812
...GFVTFS	69	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt122813
...TFSSMA	72	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28683
...TFSSMA	72	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29585
...TFSSMA	72	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt123070
...TFSSMA	72	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt123071
...KLFVGG	117	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33179
...KLFVGG	117	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt125901
...KLFVGG	117	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt125902
...LFVGGI	118	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33182
...LFVGGI	118	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt125971
...LFVGGI	118	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt125972
...HHLRDY	130	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33185
...HHLRDY	130	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt126663
...HHLRDY	130	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt126664
...SRSGRG	203	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33188
...SRSGRG	203	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt129624
...SRSGRG	203	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt129625
...YGPMKS	317	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29588
...YGPMKS	317	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt132408
...YGPMKS	317	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt133426
...GRSRY	353	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...GRSRY	353	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt83671
...GRSRY	353	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt83670

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MMP2_MOUSE	27	IGGL.\|.LSFE	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
MMP2_MOUSE	28	GGLS.\|.SFET	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
MMP2_MOUSE	46	WGKL.\|.LTDC	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
CATE_MOUSE	66	FGFV.\|.VTFS	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> ROA2_MOUSE @66
CATD_MOUSE	69	VTFS.\|.SSMA	inferred from experiment	unknown	MEROPS		Merops CATD_MOUSE -> ROA2_MOUSE @69
CATD_MOUSE	72	SSMA.\|.AEVD	inferred from experiment	unknown	MEROPS		Merops CATD_MOUSE -> ROA2_MOUSE @72
CATE_MOUSE	72	SSMA.\|.AEVD	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> ROA2_MOUSE @72
MMP2_MOUSE	117	FVGG.\|.GIKE	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
MMP2_MOUSE	118	VGGI.\|.IKED	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
MMP2_MOUSE	130	LRDY.\|.YFEE	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
MMP2_MOUSE	203	SGRG.\|.GGNF	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
CATE_MOUSE	317	PMKS.\|.SGNF	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> ROA2_MOUSE @317

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)