P01178: Oxytocin-neurophysin 1

General Information

Protein names	- Oxytocin-neurophysin 1 - OT-NPI - Oxytocin - Ocytocin - Neurophysin 1
Gene names	OXT
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P01178

5 N-termini

5 C-termini

5 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAGPSLACCL LGLLALTSAC YIQNCPLGGK RAAPDLDVRK CLPCGPGGKG RCFGPNICCA
        70         80         90        100        110        120
EELGCFVGTA EALRCQEENY LPSPCQSGQK ACGSGGRCAV LGLCCSPDGC HADPACDAEA

TFSQR

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

5 N-termini - 5 C-termini - 5 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
P01178-21-unknown	YIQNCP...	21	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC16709
P01178-24-unknown	NCPLGG...	24	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC8451
P01178-27-unknown	LGGKRA...	27	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC26684
P01178-27-unknown	LGGKRA...	27	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC27621
P01178-28-unknown	GGKRAA...	28	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC8452
P01178-32-unknown	AAPDLD...	32	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...LTSACY	20	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC16709
...ACYIQN	23	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC8451
...IQNCPL	26	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC26684
...IQNCPL	26	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC27621
...QNCPLG	27	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC8452
...TFSQR	125	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
LCAP_HUMAN	20	SACY.\|.YIQN	inferred from experiment	unknown	MEROPS		Merops LCAP_HUMAN -> NEU1_HUMAN @20
CTRC_HUMAN	23	YIQN.\|.NCPL	inferred from experiment	unknown	MEROPS	COLE PW	FOLK JE et al.:CHYMOTRYPSIN C. II. ENZYMATIC S... (S01.157)	14253411,
NEP_HUMAN	26	NCPL.\|.LGGK	inferred from experiment	unknown	MEROPS	Erdos EG	Johnson AR et al.:Enzymes in placental microvilli... (M13.001)	6093076,
PPCE_HUMAN	26	NCPL.\|.LGGK	inferred from experiment	unknown	MEROPS	Walter R	Koida M et al.:Post-proline cleaving enzyme. P... (S09.001)	12173,
CTRC_HUMAN	27	CPLG.\|.GGKR	inferred from experiment	unknown	MEROPS	COLE PW	FOLK JE et al.:CHYMOTRYPSIN C. II. ENZYMATIC S... (S01.157)	14253411,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)