P47754: F-actin-capping protein subunit alpha-2

General Information

Protein names	- F-actin-capping protein subunit alpha-2 - CapZ alpha-2
Gene names	Capza2
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	P47754

5 N-termini

4 C-termini

5 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MADLEEQLSD EEKVRIAAKF IIHAPPGEFN EVFNDVRLLL NNDNLLREGA AHAFAQYNLD
        70         80         90        100        110        120
QFTPVKIEGY EDQVLITEHG DLGNGKFLDP KNRICFKFDH LRKEATDPRP YEAENAIESW
       130        140        150        160        170        180
RTSVETALRA YVKEHYPNGV CTVYGKKVDG QQTIIACIES HQFQAKNFWN GRWRSEWKFT
       190        200        210        220        230        240
VTPSTTQVVG ILKIQVHYYE DGNVQLVSHK DIQDSLTVSN EVQTAKEFIK IVEAAENEYQ
       250        260        270        280
TAISENYQTM SDTTFKALRR QLPVTRTKID WNKILSYKIG KEMQNA

Isoforms

Sequence View

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Physiological Relevance:

Evidence Codes:

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Evidence Names:

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Protein Neighborhood

Domains & Features

5 N-termini - 4 C-termini - 5 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P47754-2-unknown	MADLEE...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P47754-2-Acetylation	ADLEEQ...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P47754-2-Acetylation	ADLEEQ...	2	acetylation-		N-TAILS		Overall CM.	auf dem Keller U.: A statistics-based platform for quantitative N-terminome...	20305283
P47754-2-Acetylation	ADLEEQ...	2	acetylation-		N-TAILS		Overall CM.	Kleifeldt O. et al.: Isotopic labeling of terminal amines in complex samples identifies...	20208520
P47754-2-Acetylation	ADLEEQ...	2	acetylation-		unknown			Kleifeldt O. et al.: N-terminome analysis of bronchoalveolar lavage fluids collected from...	20208520
P47754-29-unknown	FNEVFN...	29		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33569
P47754-30-unknown	NEVFND...	30		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29976
P47754-30-unknown	NEVFND...	30		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33570
P47754-39-unknown	LLNNDN...	39		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33571
P47754-39-unknown	LLNNDN...	39		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC28885

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...APPGEF	28	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33569
...PPGEFN	29	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29976
...PPGEFN	29	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33570
...NDVRLL	38	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33571
...NDVRLL	38	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28885
...EMQNA	286	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MMP2_MOUSE	28	PGEF.\|.FNEV	inferred from experiment	unknown	MEROPS	Overall CM	Prudova A et al.:Multiplex N-terminome analysis ... (M10.004)	20305284,
CATE_MOUSE	29	GEFN.\|.NEVF	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> CAZA2_MOUSE @29
MMP2_MOUSE	29	GEFN.\|.NEVF	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
MMP2_MOUSE	38	VRLL.\|.LLNN	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
CATD_MOUSE	38	VRLL.\|.LLNN	inferred from experiment	unknown	MEROPS	Zornig M	Melzer IM et al.:The Apaf-1-binding protein Aven... (A01.009)	22388353,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)