P62827: GTP-binding nuclear protein Ran

General Information

Protein names	- GTP-binding nuclear protein Ran - GTPase Ran - Ras-like protein TC4 - Ras-related nuclear protein
Gene names	Ran
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	P62827

10 N-termini

6 C-termini

7 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAAQGEPQVQ FKLVLVGDGG TGKTTFVKRH LTGEFEKKYV ATLGVEVHPL VFHTNRGPIK
        70         80         90        100        110        120
FNVWDTAGQE KFGGLRDGYY IQAQCAIIMF DVTSRVTYKN VPNWHRDLVR VCENIPIVLC
       130        140        150        160        170        180
GNKVDIKDRK VKAKSIVFHR KKNLQYYDIS AKSNYNFEKP FLWLARKLIG DPNLEFVAMP
       190        200        210
ALAPPEVVMD PALAAQYEHD LEVAQTTALP DEDDDL

Isoforms

Sequence View

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Evidence Names:

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Protein Neighborhood

Domains & Features

10 N-termini - 6 C-termini - 7 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P62827-2-unknown	MAAQGE...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P62827-2-Acetylation	AAQGEP...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P62827-2-Acetylation	AAQGEP...	2	acetylation-		N-TAILS		Overall CM.	auf dem Keller U.: A statistics-based platform for quantitative N-terminome...	20305283
P62827-2-Acetylation	AAQGEP...	2	acetylation-		N-TAILS		Overall CM.	Kleifeldt O. et al.: Isotopic labeling of terminal amines in complex samples identifies...	20208520
P62827-2-Acetylation	AAQGEP...	2	acetylation-		N-TAILS		Overall CM.	Prudova A.: Multiplex N-terminome analysis of MMP-2 and MMP-9...	20305284
P62827-12-unknown	KLVLVG...	12		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33703
P62827-13-unknown	LVLVGD...	13			N-TAILS		Overall CM.	auf dem Keller U.: A statistics-based platform for quantitative N-terminome...	20305283
P62827-13-unmodified	LVLVGD...	13			N-TAILS		Overall CM.	Kleifeldt O. et al.: Isotopic labeling of terminal amines in complex samples identifies...	20208520
P62827-14-unknown	VLVGDG...	14		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC28998
P62827-14-unknown	VLVGDG...	14		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC30200
P62827-16-unknown	VGDGGT...	16		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC28999
P62827-16-unknown	VGDGGT...	16		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC30201
P62827-38-unmodified	KYVATL...	38			N-TAILS		Overall CM.	Prudova A.: Multiplex N-terminome analysis of MMP-2 and MMP-9...	20305284
P62827-43-unknown	LGVEVH...	43		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33704
P62827-120-unknown	CGNKVD...	120		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29000

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...PQVQFK	11	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33703
...VQFKLV	13	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28998
...VQFKLV	13	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30200
...FKLVLV	15	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28999
...FKLVLV	15	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30201
...KYVATL	42	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33704
...IPIVLC	119	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29000
...EDDDL	216	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MMP2_MOUSE	11	VQFK.\|.KLVL	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
CATD_MOUSE	13	FKLV.\|.VLVG	inferred from experiment	unknown	MEROPS		Merops CATD_MOUSE -> RAN_MOUSE @13
CATE_MOUSE	13	FKLV.\|.VLVG	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> RAN_MOUSE @13
CATD_MOUSE	15	LVLV.\|.VGDG	inferred from experiment	unknown	MEROPS		Merops CATD_MOUSE -> RAN_MOUSE @15
CATE_MOUSE	15	LVLV.\|.VGDG	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> RAN_MOUSE @15
MMP2_MOUSE	42	VATL.\|.LGVE	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
CATD_MOUSE	119	IVLC.\|.CGNK	inferred from experiment	unknown	MEROPS		Merops CATD_MOUSE -> RAN_MOUSE @119

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)