P63101: 14-3-3 protein zeta/delta

General Information

Protein names	- 14-3-3 protein zeta/delta - Protein kinase C inhibitor protein 1 - KCIP-1 - SEZ-2
Gene names	Ywhaz
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	P63101

20 N-termini

19 C-termini

25 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MDKNELVQKA KLAEQAERYD DMAACMKSVT EQGAELSNEE RNLLSVAYKN VVGARRSSWR
        70         80         90        100        110        120
VVSSIEQKTE GAEKKQQMAR EYREKIETEL RDICNDVLSL LEKFLIPNAS QPESKVFYLK
       130        140        150        160        170        180
MKGDYYRYLA EVAAGDDKKG IVDQSQQAYQ EAFEISKKEM QPTHPIRLGL ALNFSVFYYE
       190        200        210        220        230        240
ILNSPEKACS LAKTAFDEAI AELDTLSEES YKDSTLIMQL LRDNLTLWTS DTQGDEAEAG

EGGEN

Isoforms

Sequence View

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Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

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Lab:

Protein Neighborhood

Domains & Features

20 N-termini - 19 C-termini - 25 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P63101-1-Acetylation	MDKNEL...	1	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P63101-1-Acetylation	MDKNEL...	1	acetylation-		N-TAILS		Overall CM.	Kleifeldt O. et al.: Isotopic labeling of terminal amines in complex samples identifies...	20208520
P63101-1-Acetylation	MDKNEL...	1	acetylation-		unknown			Kleifeldt O. et al.: N-terminome analysis of bronchoalveolar lavage fluids collected from...	20208520
P63101-6-unknown	LVQKAK...	6		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33741
P63101-7-unknown	VQKAKL...	7		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC30238
P63101-23-unknown	AACMKS...	23		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC30239
P63101-23-unknown	AACMKS...	23		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29024
P63101-24-unknown	ACMKSV...	24		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC30240
P63101-24-unknown	ACMKSV...	24		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29025
P63101-25-unknown	CMKSVT...	25		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29026
P63101-25-unknown	CMKSVT...	25		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33742
P63101-26-unknown	MKSVTE...	26		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC30241
P63101-26-unknown	MKSVTE...	26		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33743
P63101-26-unmodified	MKSVTE...	26			N-TAILS		Overall CM.	Prudova A.: Multiplex N-terminome analysis of MMP-2 and MMP-9...	20305284
P63101-27-unknown	KSVTEQ...	27		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC30242
P63101-27-unknown	KSVTEQ...	27		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29027
P63101-28-unknown	SVTEQG...	28		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33744
P63101-29-unknown	VTEQGA...	29		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC30243
P63101-43-unknown	LLSVAY...	43		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33745
P63101-44-unknown	LSVAYK...	44		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC30244
P63101-44-unknown	LSVAYK...	44		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29028
P63101-45-unknown	SVAYKN...	45		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC30245
P63101-45-unknown	SVAYKN...	45		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29029
P63101-67-unknown	QKTEGA...	67		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC30246
P63101-118-unknown	YLKMKG...	118		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC30247
P63101-118-unknown	YLKMKG...	118		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29030
P63101-155-unknown	ISKKEM...	155		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33746
P63101-158-unknown	KEMQPT...	158		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33747
P63101-159-unknown	EMQPTH...	159		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33748
P63101-208-unknown	EESYKD...	208			N-TAILS		Overall CM.	auf dem Keller U.: A statistics-based platform for quantitative N-terminome...	20305283
P63101-208-unknown	EESYKD...	208		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P63101-208-unknown	EESYKD...	208		inferred from similarity	unknown	UniProtKB		inferred from uniprot (by similarity)

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...MDKNEL	5	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33741
...DKNELV	6	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30238
...RYDDMA	22	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30239
...RYDDMA	22	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29024
...YDDMAA	23	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30240
...YDDMAA	23	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29025
...DDMAAC	24	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29026
...DDMAAC	24	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33742
...DMAACM	25	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30241
...DMAACM	25	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33743
...DMAACM	25	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000105988
...DMAACM	25	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30242
...DMAACM	25	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29027
...AACMKS	27	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33744
...ACMKSV	28	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30243
...NEERNL	42	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33745
...EERNLL	43	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30244
...EERNLL	43	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29028
...EERNLL	43	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000120610
...EERNLL	43	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30245
...EERNLL	43	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29029
...VSSIEQ	66	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30246
...EKIETE	88	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000115928
...ESKVFY	117	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30247
...ESKVFY	117	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29030
...QEAFEI	154	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33746
...FEISKK	157	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33747
...EISKKE	158	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33748
...EGGEN	245	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MMP2_MOUSE	5	KNEL.\|.LVQK	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
CATE_MOUSE	6	NELV.\|.VQKA	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> 1433Z_MOUSE @6
CATE_MOUSE	22	DDMA.\|.AACM	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> 1433Z_MOUSE @22
CATD_MOUSE	22	DDMA.\|.AACM	inferred from experiment	unknown	MEROPS		Merops CATD_MOUSE -> 1433Z_MOUSE @22
CATE_MOUSE	23	DMAA.\|.ACMK	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> 1433Z_MOUSE @23
CATD_MOUSE	23	DMAA.\|.ACMK	inferred from experiment	unknown	MEROPS		Merops CATD_MOUSE -> 1433Z_MOUSE @23
CATD_MOUSE	24	MAAC.\|.CMKS	inferred from experiment	unknown	MEROPS		Merops CATD_MOUSE -> 1433Z_MOUSE @24
MMP2_MOUSE	24	MAAC.\|.CMKS	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
CATE_MOUSE	25	AACM.\|.MKSV	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> 1433Z_MOUSE @25
MMP2_MOUSE	25	AACM.\|.MKSV	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
CATE_MOUSE	26	ACMK.\|.KSVT	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> 1433Z_MOUSE @26
CATD_MOUSE	26	ACMK.\|.KSVT	inferred from experiment	unknown	MEROPS		Merops CATD_MOUSE -> 1433Z_MOUSE @26
MMP2_MOUSE	27	CMKS.\|.SVTE	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
CATE_MOUSE	28	MKSV.\|.VTEQ	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> 1433Z_MOUSE @28
MMP2_MOUSE	42	ERNL.\|.LLSV	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
CATE_MOUSE	43	RNLL.\|.LSVA	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> 1433Z_MOUSE @43
CATD_MOUSE	43	RNLL.\|.LSVA	inferred from experiment	unknown	MEROPS	Zornig M	Melzer IM et al.:The Apaf-1-binding protein Aven... (A01.009)	22388353,
CATE_MOUSE	44	NLLS.\|.SVAY	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> 1433Z_MOUSE @44
CATD_MOUSE	44	NLLS.\|.SVAY	inferred from experiment	unknown	MEROPS		Merops CATD_MOUSE -> 1433Z_MOUSE @44
CATE_MOUSE	66	SIEQ.\|.QKTE	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> 1433Z_MOUSE @66
CATE_MOUSE	117	KVFY.\|.YLKM	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> 1433Z_MOUSE @117
CATD_MOUSE	117	KVFY.\|.YLKM	inferred from experiment	unknown	MEROPS		Merops CATD_MOUSE -> 1433Z_MOUSE @117
MMP2_MOUSE	154	AFEI.\|.ISKK	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
MMP2_MOUSE	157	ISKK.\|.KEMQ	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
MMP2_MOUSE	158	SKKE.\|.EMQP	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)