Q8CDN6: Thioredoxin-like protein 1

General Information

Protein names	- Thioredoxin-like protein 1 - 32 kDa thioredoxin-related protein
Gene names	Txnl1
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q8CDN6

6 N-termini

5 C-termini

4 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MVGVKPVGSD PDFQPELSGA GSRLAVVKFT MRGCGPCLRI APAFSSMSNK YPQAVFLEVD
        70         80         90        100        110        120
VHQCQGTAAT NNISATPTFL FFRNKVRIDQ YQGADAVGLE EKIKQHLEND PGSNEDADIP
       130        140        150        160        170        180
KGYMDLMPFI NKAGCECLNE SDEHGFDNCL RKDMSFLESD CDEQLLITVA FNQPVKLYSM
       190        200        210        220        230        240
KFQGPDNGQG PKYVKIFINL PRSMDFEEAE RSEPTQALEL TEDDIKEDGI VPLRYVKFQN
       250        260        270        280
VNSVTLFVQS NQGEEETTRI SYFTFIGTPV QATNMNDFKR VVGKKGESH

Isoforms

Sequence View

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(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

6 N-termini - 5 C-termini - 4 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q8CDN6-2-unmodified	VGVKPV...	2		N-TAILS		Overall CM.	Kleifeldt O. et al.: Isotopic labeling of terminal amines in complex samples identifies...	20208520
Q8CDN6-2-unmodified	VGVKPV...	2		N-TAILS		Overall CM.	Prudova A.: Multiplex N-terminome analysis of MMP-2 and MMP-9...	20305284
Q8CDN6-2-unknown	VGVKPV...	2	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q8CDN6-2-unknown	VGVKPV...	2	inferred from similarity	unknown	UniProtKB		inferred from uniprot (by similarity)
Q8CDN6-2-unknown	VGVKPV...	2		N-TAILS		Overall CM.	auf dem Keller U.: A statistics-based platform for quantitative N-terminome...	20305283
Q8CDN6-25-unknown	AVVKFT...	25	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC30784
Q8CDN6-220-unknown	LTEDDI...	220	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC34094
Q8CDN6-263-unknown	FTFIGT...	263	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC34095
Q8CDN6-266-unknown	IGTPVQ...	266	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29243

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...AGSRLA	24	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30784
...TQALEL	219	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34094
...TRISYF	262	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34095
...SYFTFI	265	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29243
...KGESH	289	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATE_MOUSE	24	SRLA.\|.AVVK	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> TXNL1_MOUSE @24
MMP2_MOUSE	219	ALEL.\|.LTED	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
MMP2_MOUSE	262	ISYF.\|.FTFI	inferred from experiment	unknown	MEROPS		Merops MMP2_MOUSE -> TXNL1_MOUSE @262
CATD_MOUSE	265	FTFI.\|.IGTP	inferred from experiment	unknown	MEROPS		Merops CATD_MOUSE -> TXNL1_MOUSE @265

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)