Q9BSU1: UPF0183 protein C16orf70

General Information

Protein names	- UPF0183 protein C16orf70
Gene names	C16orf70
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9BSU1

4 N-termini

3 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MLDLEVVPER SLGNEQWEFT LGMPLAQAVA ILQKHCRIIK NVQVLYSEQS PLSHDLILNL
        70         80         90        100        110        120
TQDGIKLMFD AFNQRLKVIE VCDLTKVKLK YCGVHFNSQA IAPTIEQIDQ SFGATHPGVY
       130        140        150        160        170        180
NSAEQLFHLN FRGLSFSFQL DSWTEAPKYE PNFAHGLASL QIPHGATVKR MYIYSGNSLQ
       190        200        210        220        230        240
DTKAPMMPLS CFLGNVYAES VDVLRDGTGP AGLRLRLLAA GCGPGLLADA KMRVFERSVY
       250        260        270        280        290        300
FGDSCQDVLS MLGSPHKVFY KSEDKMKIHS PSPHKQVPSK CNDYFFNYFT LGVDILFDAN
       310        320        330        340        350        360
THKVKKFVLH TNYPGHYNFN IYHRCEFKIP LAIKKENADG QTETCTTYSK WDNIQELLGH
       370        380        390        400        410        420
PVEKPVVLHR SSSPNNTNPF GSTFCFGLQR MIFEVMQNNH IASVTLYGPP RPGSHLRTAE

LP

Isoforms

- Isoform 2 of UPF0183 protein C16orf70

Sequence View

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Protein Neighborhood

Domains & Features

4 N-termini - 3 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q9BSU1-1-unknown	MLDLEV...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9BSU1-1-unknown	MLDLEV...	1		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
Q9BSU1-1-unknown	MLDLEV...	1		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
Q9BSU1-1-	MLDLEV...	1		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
Q9BSU1-1-	MLDLEV...	1		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q9BSU1-1-	MLDLEV...	1		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q9BSU1-1-	MLDLEV...	1		Subtiligase Based Positive Selection		Wells	MM1SDBJurkat_Untreated	23264352
Q9BSU1-1-	MLDLEV...	1		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
Q9BSU1-1-	MLDLEV...	1		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
Q9BSU1-1-	MLDLEV...	1		N-TAILS		Overall Laboratory	Lange_Huesgen_et_al-RBC
Q9BSU1-23-unknown	MPLAQA...	23	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt71488
Q9BSU1-192-unknown	FLGNVY...	192	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC6728

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...LQDTKA	183	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt67106
...MPLSCF	191	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC6728
...TAELP	422	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATL1_HUMAN	191	LSCF.\|.FLGN	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)