TopFIND 4.0

Q9Y6D0: Selenoprotein K {ECO:0000303|PubMed:27645994}

General Information

Protein names	- Selenoprotein K {ECO:0000303\|PubMed:27645994} - SelK {ECO:0000303\|PubMed:12775843}
Gene names	SELK
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9Y6D0

3

N-termini

2

C-termini

1

Cleavages

0

Substrates

Sequence

10 20 30 40 50 60
MVYISNGQVL DSRSQSPWRL SLITDFFWGI AEFVVLFFKT LLQQDVKKRR SYGNSSDSRY
70 80 90
DDGRGPPGNP PRRMGRINHL RGPSPPPMAG GUGR

Isoforms

Sequence View

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Physiological Relevance:

Evidence Codes:

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Protease Assignment Confidence:

Evidence Names:

Database:

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Protein Neighborhood

Domains & Features

3 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q9Y6D0-2-unknown	VYISNG...	2		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9Y6D0-2-unknown	VYISNG...	2			unknown			Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
Q9Y6D0-2-	VYISNG...	2			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
Q9Y6D0-2-	VYISNG...	2			Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
Q9Y6D0-2-	VYISNG...	2			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q9Y6D0-2-	VYISNG...	2			Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q9Y6D0-2-	VYISNG...	2			Subtiligase Based Positive Selection		Wells	MM1SDBJurkat_Untreated	23264352
Q9Y6D0-2-	VYISNG...	2			Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
Q9Y6D0-2-	VYISNG...	2			Subtiligase Based Positive Selection		Wells	THP_untreated	23264352
Q9Y6D0-2-	VYISNG...	2			Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
Q9Y6D0-82-unknown	GPSPPP...	82		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC1078

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...INHLRG	81	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC1078
	...GGUGR	94	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CAN2_HUMAN	81	HLRG.\|.GPSP	inferred from experiment	unknown	MEROPS	Hoffmann PR	Huang Z et al.:Selenoprotein K is a novel targ... (C02.002)	21849499,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)