TopFIND 4.0

Q9Y5Y6: Suppressor of tumorigenicity 14 protein

General Information

Protein names
- Suppressor of tumorigenicity 14 protein
- 3.4.21.109
- Matriptase
- Membrane-type serine protease 1
- MT-SP1
- Prostamin
- Serine protease 14
- Serine protease TADG-15
- Tumor-associated differentially-expressed gene 15 protein
Gene names ST14
Organism Homo sapiens
Protease Family S01.302
Protease ID S01.302
Chromosome location
UniProt ID Q9Y5Y6

3

N-termini

3

C-termini

2

Cleavages

14

Substrates

Sequence

        10         20         30         40         50         60 
MGSDRARKGG GGPKDFGAGL KYNSRHEKVN GLEEGVEFLP VNNVKKVEKH GPGRWVVLAA 
        70         80         90        100        110        120 
VLIGLLLVLL GIGFLVWHLQ YRDVRVQKVF NGYMRITNEN FVDAYENSNS TEFVSLASKV 
       130        140        150        160        170        180 
KDALKLLYSG VPFLGPYHKE SAVTAFSEGS VIAYYWSEFS IPQHLVEEAE RVMAEERVVM 
       190        200        210        220        230        240 
LPPRARSLKS FVVTSVVAFP TDSKTVQRTQ DNSCSFGLHA RGVELMRFTT PGFPDSPYPA 
       250        260        270        280        290        300 
HARCQWALRG DADSVLSLTF RSFDLASCDE RGSDLVTVYN TLSPMEPHAL VQLCGTYPPS 
       310        320        330        340        350        360 
YNLTFHSSQN VLLITLITNT ERRHPGFEAT FFQLPRMSSC GGRLRKAQGT FNSPYYPGHY 
       370        380        390        400        410        420 
PPNIDCTWNI EVPNNQHVKV RFKFFYLLEP GVPAGTCPKD YVEINGEKYC GERSQFVVTS 
       430        440        450        460        470        480 
NSNKITVRFH SDQSYTDTGF LAEYLSYDSS DPCPGQFTCR TGRCIRKELR CDGWADCTDH 
       490        500        510        520        530        540 
SDELNCSCDA GHQFTCKNKF CKPLFWVCDS VNDCGDNSDE QGCSCPAQTF RCSNGKCLSK 
       550        560        570        580        590        600 
SQQCNGKDDC GDGSDEASCP KVNVVTCTKH TYRCLNGLCL SKGNPECDGK EDCSDGSDEK 
       610        620        630        640        650        660 
DCDCGLRSFT RQARVVGGTD ADEGEWPWQV SLHALGQGHI CGASLISPNW LVSAAHCYID 
       670        680        690        700        710        720 
DRGFRYSDPT QWTAFLGLHD QSQRSAPGVQ ERRLKRIISH PFFNDFTFDY DIALLELEKP 
       730        740        750        760        770        780 
AEYSSMVRPI CLPDASHVFP AGKAIWVTGW GHTQYGGTGA LILQKGEIRV INQTTCENLL 
       790        800        810        820        830        840 
PQQITPRMMC VGFLSGGVDS CQGDSGGPLS SVEADGRIFQ AGVVSWGDGC AQRNKPGVYT 
       850    
RLPLFRDWIK ENTGV

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

3 N-termini - 3 C-termini - 2 Cleavages - 14 Substrates

N-termini

C-termini

Cleavages

Substrates